282913

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907-MazE
Location 1237655..1238220 Replicon chromosome
Accession NZ_CP126446
Organism Pontibacillus chungwhensis strain HN14

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag QNI29_RS06460 Protein ID WP_231418086.1
Coordinates 1237891..1238220 (+) Length 110 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag QNI29_RS06455 Protein ID WP_231418087.1
Coordinates 1237655..1237891 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QNI29_RS06430 (QNI29_06430) 1232730..1233983 + 1254 WP_231418092.1 aminopeptidase -
QNI29_RS06435 (QNI29_06435) 1234127..1234657 + 531 WP_231418091.1 GrpB family protein -
QNI29_RS06440 (QNI29_06440) 1235606..1236271 + 666 WP_231418090.1 Type 1 glutamine amidotransferase-like domain-containing protein -
QNI29_RS06445 (QNI29_06445) 1236297..1236737 + 441 WP_231418089.1 GNAT family N-acetyltransferase -
QNI29_RS06450 (QNI29_06450) 1236874..1237491 + 618 WP_231418088.1 hypothetical protein -
QNI29_RS06455 (QNI29_06455) 1237655..1237891 + 237 WP_231418087.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
QNI29_RS06460 (QNI29_06460) 1237891..1238220 + 330 WP_231418086.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
QNI29_RS06465 (QNI29_06465) 1238784..1239959 + 1176 WP_231418085.1 MFS transporter -
QNI29_RS06470 (QNI29_06470) 1240204..1240662 + 459 WP_231418084.1 hypothetical protein -
QNI29_RS06475 (QNI29_06475) 1241023..1241427 + 405 WP_231418083.1 hypothetical protein -
QNI29_RS06480 (QNI29_06480) 1241465..1241869 + 405 WP_231418082.1 ester cyclase -
QNI29_RS06485 (QNI29_06485) 1241923..1242612 + 690 WP_231418081.1 DNA alkylation repair protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(5-105)

Antitoxin

Antitoxin PemI-like

(1-76)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 12138.99 Da        Isoelectric Point: 9.1934

>T282913 WP_231418086.1 NZ_CP126446:1237891-1238220 [Pontibacillus chungwhensis]
VNAPKRGDLVYLTFDPQAGHEQRGRRPGIVLSPQPFNNKTGFALCCPITNQQKGYPFEVSLPVNRKISGVILTDQIKSLD
WKARKISLVDEAPNSVVQSCLELVKTYLD

Download         Length: 330 bp

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8609.75 Da        Isoelectric Point: 4.4607

>AT282913 WP_231418087.1 NZ_CP126446:1237655-1237891 [Pontibacillus chungwhensis]
MSTKIQKLGDGLAIRIPPHVAEQLQVQQGSEVEIKIEGGIVTLQPVNRKLDLNELLSEITPENRHDEIDVGSEGNEKL

Download         Length: 237 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References