Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1944693..1944964 Replicon chromosome
Accession NZ_CP126348
Organism Escherichia coli strain NN5

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1944823..1944926 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1944693..1944964 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QN227_RS09285 1941248..1941910 - 663 WP_000944256.1 exodeoxyribonuclease X -
QN227_RS09290 1941934..1942590 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
QN227_RS09295 1942692..1942922 - 231 WP_000916763.1 DNA polymerase III subunit theta -
QN227_RS09300 1943061..1943435 + 375 WP_000204699.1 CopC domain-containing protein YobA -
QN227_RS09305 1943439..1944311 + 873 WP_000879285.1 copper homeostasis membrane protein CopD -
QN227_RS09310 1944324..1944665 + 342 WP_000976492.1 YebY family protein -
- 1944693..1944964 - 272 - - Antitoxin
- 1944823..1944926 + 104 - - Toxin
QN227_RS09315 1945061..1945717 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
QN227_RS09320 1945718..1945909 - 192 WP_001296140.1 YebW family protein -
QN227_RS09325 1946014..1946250 - 237 WP_001295499.1 YebV family protein -
QN227_RS09330 1946368..1947807 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T282899 NZ_CP126348:1944823-1944926 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT282899 NZ_CP126348:c1944964-1944693 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCTAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References