Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 83755..84290 Replicon plasmid pDX6A
Accession NZ_CP126346
Organism Escherichia coli strain DX6

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QN223_RS23910 Protein ID WP_032206513.1
Coordinates 83755..84042 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QN223_RS23915 Protein ID WP_032206515.1
Coordinates 84039..84290 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QN223_RS23900 (QN223_23900) 79036..82533 + 3498 WP_001038839.1 autotransporter outer membrane beta-barrel domain-containing protein -
QN223_RS23905 (QN223_23905) 82698..83395 + 698 WP_103215986.1 IS1-like element IS1A family transposase -
QN223_RS23910 (QN223_23910) 83755..84042 - 288 WP_032206513.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QN223_RS23915 (QN223_23915) 84039..84290 - 252 WP_032206515.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QN223_RS23920 (QN223_23920) 84873..88841 + 3969 Protein_87 helicase-related protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Mobilizable plasmid blaTEM-1A / tet(A) / floR - 1..122915 122915


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11130.20 Da        Isoelectric Point: 10.5833

>T282890 WP_032206513.1 NZ_CP126346:c84042-83755 [Escherichia coli]
MTYTVKFRDDALKEWLRLDKTIQQQFAKKLKKCSENPHIASAKLRGLKDCYKIKLRASGFRLVYQIIDDMLIIAVVAVGK
RERSNVYHLASERMK

Download         Length: 288 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9161.35 Da        Isoelectric Point: 4.0927

>AT282890 WP_032206515.1 NZ_CP126346:c84290-84039 [Escherichia coli]
MPSIILSDTSASVSELKKNPMATVSAGEGYPVAILNRNQPAFYCVPAELYERMLDALDDQELVKLVTERSSQSLHDVDLD
SYL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References