Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2215691..2215962 | Replicon | chromosome |
| Accession | NC_018650 | ||
| Organism | Escherichia coli O104:H4 str. 2009EL-2050 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2215821..2215924 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2215691..2215962 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| O3M_RS11095 | 2212246..2212908 | - | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
| O3M_RS11100 | 2212932..2213588 | - | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein | - |
| O3M_RS11105 | 2213690..2213920 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| O3M_RS11110 | 2214059..2214433 | + | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| O3M_RS11115 | 2214437..2215309 | + | 873 | WP_000879280.1 | copper homeostasis membrane protein CopD | - |
| O3M_RS11120 | 2215322..2215663 | + | 342 | WP_000976472.1 | YebY family protein | - |
| - | 2215691..2215962 | - | 272 | - | - | Antitoxin |
| - | 2215821..2215924 | + | 104 | - | - | Toxin |
| O3M_RS11130 | 2216059..2216715 | + | 657 | WP_000812712.1 | protein-serine/threonine phosphatase | - |
| O3M_RS11135 | 2216716..2216907 | - | 192 | WP_001296140.1 | YebW family protein | - |
| O3M_RS11140 | 2217012..2217248 | - | 237 | WP_001295499.1 | DUF1480 family protein | - |
| O3M_RS11145 | 2217366..2218805 | - | 1440 | WP_000057022.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2137953..2231801 | 93848 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T28287 NC_018650:2215821-2215924 [Escherichia coli O104:H4 str. 2009EL-2050]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT
Antitoxin
Download Length: 272 bp
>AT28287 NC_018650:c2215962-2215691 [Escherichia coli O104:H4 str. 2009EL-2050]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
