Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /Acetyltransf_4(toxin) |
| Location | 1730356..1731764 | Replicon | chromosome |
| Accession | NZ_CP126342 | ||
| Organism | Pseudomonas otitidis strain TL17 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | QN096_RS08145 | Protein ID | WP_142011214.1 |
| Coordinates | 1730356..1730925 (+) | Length | 190 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | A0A542V6R8 |
| Locus tag | QN096_RS08150 | Protein ID | WP_074968953.1 |
| Coordinates | 1730922..1731764 (+) | Length | 281 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QN096_RS08135 (QN096_08135) | 1725357..1726556 | - | 1200 | WP_182852135.1 | GGDEF domain-containing protein | - |
| QN096_RS08140 (QN096_08140) | 1726644..1730120 | - | 3477 | WP_044406195.1 | PAS domain-containing hybrid sensor histidine kinase/response regulator | - |
| QN096_RS08145 (QN096_08145) | 1730356..1730925 | + | 570 | WP_142011214.1 | GNAT family protein | Toxin |
| QN096_RS08150 (QN096_08150) | 1730922..1731764 | + | 843 | WP_074968953.1 | AraC family transcriptional regulator | Antitoxin |
| QN096_RS08155 (QN096_08155) | 1731802..1732515 | + | 714 | WP_284548426.1 | AzlC family ABC transporter permease | - |
| QN096_RS08160 (QN096_08160) | 1732515..1732844 | + | 330 | WP_172432980.1 | AzlD domain-containing protein | - |
| QN096_RS08165 (QN096_08165) | 1732975..1734849 | + | 1875 | WP_236212122.1 | MFS transporter | - |
| QN096_RS08170 (QN096_08170) | 1734903..1735217 | - | 315 | WP_044406178.1 | quaternary ammonium compound efflux SMR transporter SugE | - |
| QN096_RS08175 (QN096_08175) | 1735381..1736334 | - | 954 | WP_044406176.1 | bile acid:sodium symporter family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 190 a.a. Molecular weight: 21147.17 Da Isoelectric Point: 7.4044
>T282844 WP_142011214.1 NZ_CP126342:1730356-1730925 [Pseudomonas otitidis]
MFNPQPVTLQRGALRLEPLGEADVSELAALAEANRNELVYMSGPLRPDWYRQGIAQQREGQAVVFAIRLGDRLVGTSRFA
EFMPALPAVEIGWTWLAGSEHGTGLNASIKYLMLRHAFEEWQVVRVQLKTAGSNLRSQRAIEKLGAVREGVLRNHRRLAD
GRLDDSVMFSITDHEWPAVKQALEAAFVQ
MFNPQPVTLQRGALRLEPLGEADVSELAALAEANRNELVYMSGPLRPDWYRQGIAQQREGQAVVFAIRLGDRLVGTSRFA
EFMPALPAVEIGWTWLAGSEHGTGLNASIKYLMLRHAFEEWQVVRVQLKTAGSNLRSQRAIEKLGAVREGVLRNHRRLAD
GRLDDSVMFSITDHEWPAVKQALEAAFVQ
Download Length: 570 bp
Antitoxin
Download Length: 281 a.a. Molecular weight: 31273.53 Da Isoelectric Point: 9.0216
>AT282844 WP_074968953.1 NZ_CP126342:1730922-1731764 [Pseudomonas otitidis]
MSTGGERTRFWQASALSGVELLHARYIQHRFSPHVHEGYVFTILESGAQRFRHRGSDHLAAVGSMVLINPDELHTGSKAH
EEGWRYRGFYPDLHRVTDVLDELEIATGGLPTFADSVLHDPEVTRRFLDLHCLLERNASALEQQVAWREAILLLFSRHAR
IGAPRPAGQEPQAVALAREVLAARLASPPSLEELAALVGLSPFHFARVFQRATGMPPHAWLKQRRLEQARAMLRSGCAPL
SVAMQLGFADQSHLTRQFKQTYGVGPGEYRTASARSFKTD
MSTGGERTRFWQASALSGVELLHARYIQHRFSPHVHEGYVFTILESGAQRFRHRGSDHLAAVGSMVLINPDELHTGSKAH
EEGWRYRGFYPDLHRVTDVLDELEIATGGLPTFADSVLHDPEVTRRFLDLHCLLERNASALEQQVAWREAILLLFSRHAR
IGAPRPAGQEPQAVALAREVLAARLASPPSLEELAALVGLSPFHFARVFQRATGMPPHAWLKQRRLEQARAMLRSGCAPL
SVAMQLGFADQSHLTRQFKQTYGVGPGEYRTASARSFKTD
Download Length: 843 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|