Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4113947..4114607 Replicon chromosome
Accession NZ_CP126341
Organism Enterobacter cloacae strain TL15

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag QN095_RS19470 Protein ID WP_284557610.1
Coordinates 4113947..4114360 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A5E1AG01
Locus tag QN095_RS19475 Protein ID WP_013098615.1
Coordinates 4114341..4114607 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QN095_RS19450 (QN095_19450) 4109940..4111673 - 1734 WP_029883158.1 single-stranded-DNA-specific exonuclease RecJ -
QN095_RS19455 (QN095_19455) 4111679..4112392 - 714 WP_013098611.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
QN095_RS19460 (QN095_19460) 4112421..4113317 - 897 WP_013098612.1 site-specific tyrosine recombinase XerD -
QN095_RS19465 (QN095_19465) 4113419..4113940 + 522 WP_161669779.1 flavodoxin FldB -
QN095_RS19470 (QN095_19470) 4113947..4114360 - 414 WP_284557610.1 protein YgfX Toxin
QN095_RS19475 (QN095_19475) 4114341..4114607 - 267 WP_013098615.1 FAD assembly factor SdhE Antitoxin
QN095_RS19480 (QN095_19480) 4114902..4115882 + 981 WP_023620448.1 tRNA-modifying protein YgfZ -
QN095_RS19485 (QN095_19485) 4115992..4116651 - 660 WP_003863433.1 hemolysin III family protein -
QN095_RS19490 (QN095_19490) 4116917..4117648 + 732 WP_020687085.1 MurR/RpiR family transcriptional regulator -
QN095_RS19495 (QN095_19495) 4117764..4119197 + 1434 WP_284557611.1 6-phospho-beta-glucosidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16278.25 Da        Isoelectric Point: 10.5699

>T282841 WP_284557610.1 NZ_CP126341:c4114360-4113947 [Enterobacter cloacae]
VVLWQSDLRVSWRSQWMSLLLHGLVAAFVLLMPWPLSYTPLWLLLLSFVVFDSVRSQRRINARQGEIKLLMDSRLRWQDK
EWDILGMPWMLSSGMMLRLRQVGGGKCQHLWLAADSMDIAEWRELRRMLLQQQPTQE

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10569.05 Da        Isoelectric Point: 5.1456

>AT282841 WP_013098615.1 NZ_CP126341:c4114607-4114341 [Enterobacter cloacae]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDEDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A5E1AG01

References