Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 408449..409252 Replicon chromosome
Accession NZ_CP126341
Organism Enterobacter cloacae strain TL15

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag QN095_RS01930 Protein ID WP_284557665.1
Coordinates 408449..408829 (-) Length 127 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag QN095_RS01935 Protein ID WP_284557666.1
Coordinates 408887..409252 (-) Length 122 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QN095_RS01930 (QN095_01930) 408449..408829 - 381 WP_284557665.1 TA system toxin CbtA family protein Toxin
QN095_RS01935 (QN095_01935) 408887..409252 - 366 WP_284557666.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
QN095_RS01940 (QN095_01940) 409275..409496 - 222 WP_284557667.1 DUF987 domain-containing protein -
QN095_RS01945 (QN095_01945) 409516..409995 - 480 WP_262812739.1 DNA repair protein RadC -
QN095_RS01950 (QN095_01950) 410007..410483 - 477 WP_284557668.1 antirestriction protein -
QN095_RS01955 (QN095_01955) 410742..411560 - 819 WP_284557669.1 DUF932 domain-containing protein -
QN095_RS01960 (QN095_01960) 411940..412566 - 627 WP_284557670.1 hypothetical protein -
QN095_RS01965 (QN095_01965) 412572..413123 - 552 WP_284557671.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-109)

Antitoxin

Antitoxin CbeA

(15-114)


Sequences

Toxin        


Download         Length: 127 a.a.        Molecular weight: 14167.28 Da        Isoelectric Point: 9.6236

>T282832 WP_284557665.1 NZ_CP126341:c408829-408449 [Enterobacter cloacae]
MQTLSAIPTRKAPPHPTPVEIWQQLLTYLLERHYGLSLHDTQFGDGNVIQQHIDAGISLADALNFLVEKSELVRIDRPGF
SFHLQSAFIGTIDILRARRATGLMQRFGYKRITHIIAGKAAQESHP

Download         Length: 381 bp

Antitoxin


Download         Length: 122 a.a.        Molecular weight: 13426.25 Da        Isoelectric Point: 6.7432

>AT282832 WP_284557666.1 NZ_CP126341:c409252-408887 [Enterobacter cloacae]
MHSTTNAANHDSAEPWWGLRRNITPCFGARLVQEGNRLHYLADRASIAGTFSDADLRHLDQAFPVLLKQLELMLVSGELT
PRHQHSVTLYAKGLTCDADTLGSCGYLYIAIYPTEGISILR

Download         Length: 366 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References