Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3476564..3477230 Replicon chromosome
Accession NZ_CP126339
Organism Atlantibacter hermannii strain TL13

Toxin (Protein)


Gene name cptA Uniprot ID A0A447LT15
Locus tag QN094_RS16150 Protein ID WP_040459615.1
Coordinates 3476564..3476983 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID H5V069
Locus tag QN094_RS16155 Protein ID WP_002434469.1
Coordinates 3476964..3477230 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QN094_RS16130 (QN094_16130) 3472556..3474289 - 1734 WP_148051815.1 single-stranded-DNA-specific exonuclease RecJ -
QN094_RS16135 (QN094_16135) 3474293..3475012 - 720 WP_002434476.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
QN094_RS16140 (QN094_16140) 3475038..3475937 - 900 WP_002434475.1 site-specific tyrosine recombinase XerD -
QN094_RS16145 (QN094_16145) 3476039..3476560 + 522 WP_002434473.1 flavodoxin FldB -
QN094_RS16150 (QN094_16150) 3476564..3476983 - 420 WP_040459615.1 protein YgfX Toxin
QN094_RS16155 (QN094_16155) 3476964..3477230 - 267 WP_002434469.1 FAD assembly factor SdhE Antitoxin
QN094_RS16160 (QN094_16160) 3477489..3478475 + 987 WP_043865941.1 tRNA-modifying protein YgfZ -
QN094_RS16165 (QN094_16165) 3478631..3479290 - 660 WP_002434465.1 hemolysin III family protein -
QN094_RS16170 (QN094_16170) 3479420..3479731 - 312 WP_284556470.1 N(4)-acetylcytidine aminohydrolase -
QN094_RS16175 (QN094_16175) 3479844..3480581 + 738 WP_002434460.1 MurR/RpiR family transcriptional regulator -
QN094_RS16180 (QN094_16180) 3480708..3482141 + 1434 WP_148053059.1 6-phospho-beta-glucosidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 16511.44 Da        Isoelectric Point: 10.5604

>T282828 WP_040459615.1 NZ_CP126339:c3476983-3476564 [Atlantibacter hermannii]
VVLWQSDLRVSWRAQWFSLMLHGIVAAIILLLPWPLSYMPLWLILLSLVVFDCVRSQRRIHSLQGEVKLTIDYRLRWQGI
EWELTAAPWMLQSGMLLRLRHPDTHRSQHLWLAADSMDAGEWRDLRRILMQQPQSGRHP

Download         Length: 420 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10549.05 Da        Isoelectric Point: 5.6178

>AT282828 WP_002434469.1 NZ_CP126339:c3477230-3476964 [Atlantibacter hermannii]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDTLSDDDKRVFIRLLECDDPDLFNWLMNHGKPADSELQRMVQMIQTRN
RDRGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A447LT15

Antitoxin

Source ID Structure
AlphaFold DB H5V069

References