Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 3113313..3113956 Replicon chromosome
Accession NZ_CP126339
Organism Atlantibacter hermannii strain TL13

Toxin (Protein)


Gene name vagD Uniprot ID -
Locus tag QN094_RS14545 Protein ID WP_284555104.1
Coordinates 3113313..3113729 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag QN094_RS14550 Protein ID WP_284555105.1
Coordinates 3113726..3113956 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QN094_RS14540 (QN094_14540) 3111940..3113052 + 1113 WP_284555103.1 EAL domain-containing protein -
QN094_RS14545 (QN094_14545) 3113313..3113729 - 417 WP_284555104.1 type II toxin-antitoxin system VapC family toxin Toxin
QN094_RS14550 (QN094_14550) 3113726..3113956 - 231 WP_284555105.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
QN094_RS14555 (QN094_14555) 3114553..3114900 + 348 WP_284555106.1 hypothetical protein -
QN094_RS14560 (QN094_14560) 3114950..3115501 + 552 WP_284555107.1 hypothetical protein -
QN094_RS14565 (QN094_14565) 3115601..3116329 + 729 WP_284555108.1 hypothetical protein -
QN094_RS14570 (QN094_14570) 3116342..3117121 + 780 WP_284555109.1 site-specific integrase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3098968..3116329 17361


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-129)

Antitoxin

SpoVT-AbrB domain

(7-50)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15000.28 Da        Isoelectric Point: 7.8596

>T282827 WP_284555104.1 NZ_CP126339:c3113729-3113313 [Atlantibacter hermannii]
VNKTYMLDTNICSFIMREQPEAVLKRLEQAVLRNNRIVVSAITYAEMRFGATGPKASPRHTELVDAFCARLDAVLPWDRA
AVDATTEIKVALRLAGTPIGPNDSAIAGHAIAAGAVLVTNNVREFARVPGLTPEDWTK

Download         Length: 417 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8744.86 Da        Isoelectric Point: 4.4992

>AT282827 WP_284555105.1 NZ_CP126339:c3113956-3113726 [Atlantibacter hermannii]
MRTVSIFKNGNNRAIRLPRDLDFEGVSELEIVREGDRIILRPVRPTWGSFAQLEKADPDFMAEREDVVSDEGRVDL

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References