Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 1107496..1108117 Replicon chromosome
Accession NZ_CP126339
Organism Atlantibacter hermannii strain TL13

Toxin (Protein)


Gene name Hha Uniprot ID H5UYE2
Locus tag QN094_RS05200 Protein ID WP_001291435.1
Coordinates 1107496..1107714 (-) Length 73 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID -
Locus tag QN094_RS05205 Protein ID WP_043866710.1
Coordinates 1107743..1108117 (-) Length 125 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QN094_RS05165 (QN094_05165) 1102965..1103345 + 381 WP_251848762.1 hypothetical protein -
QN094_RS05170 (QN094_05170) 1103718..1103969 + 252 WP_148052435.1 hypothetical protein -
QN094_RS05175 (QN094_05175) 1103966..1104184 + 219 WP_002463728.1 hypothetical protein -
QN094_RS05180 (QN094_05180) 1104323..1105873 - 1551 WP_284556170.1 EAL domain-containing protein -
QN094_RS05185 (QN094_05185) 1106128..1106388 + 261 WP_002463724.1 type B 50S ribosomal protein L31 -
QN094_RS05190 (QN094_05190) 1106391..1106531 + 141 WP_061708247.1 type B 50S ribosomal protein L36 -
QN094_RS05195 (QN094_05195) 1106567..1107034 - 468 WP_002463722.1 YlaC family protein -
QN094_RS05200 (QN094_05200) 1107496..1107714 - 219 WP_001291435.1 HHA domain-containing protein Toxin
QN094_RS05205 (QN094_05205) 1107743..1108117 - 375 WP_043866710.1 Hha toxicity modulator TomB Antitoxin
QN094_RS05210 (QN094_05210) 1108589..1111738 - 3150 WP_002463716.1 multidrug efflux RND transporter permease subunit AcrB -
QN094_RS05215 (QN094_05215) 1111761..1112957 - 1197 WP_002463714.1 multidrug efflux RND transporter periplasmic adaptor subunit AcrA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(13-69)

Antitoxin

Biofilm formation regulator YbaJ

(1-116)


Sequences

Toxin        


Download         Length: 73 a.a.        Molecular weight: 8628.00 Da        Isoelectric Point: 8.9008

>T282821 WP_001291435.1 NZ_CP126339:c1107714-1107496 [Atlantibacter hermannii]
MSEKPLTKTDYLMRLRRCQTIDTLERVIEKNKYELSDNELAVFYSAADHRLAELTMNKLYDKIPSSVWKFIR

Download         Length: 219 bp

Antitoxin


Download         Length: 125 a.a.        Molecular weight: 14380.16 Da        Isoelectric Point: 5.1259

>AT282821 WP_043866710.1 NZ_CP126339:c1108117-1107743 [Atlantibacter hermannii]
MDEYSPKRHDIAQLKFLCENLYHDCLITLGDSNHGWVNDPTSAINLQLNELIEHIASFALNYKIKHDEDNALIEHVDEYL
DDTFMLFSNYGISAQDLQKWRKSGNRLFRCFVNVSKANPVSLSF

Download         Length: 375 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
PDB 2MW2
PDB 1JW2

Antitoxin

Source ID Structure

References