Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 544044..544747 Replicon chromosome
Accession NZ_CP126339
Organism Atlantibacter hermannii strain TL13

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag QN094_RS02620 Protein ID WP_049123929.1
Coordinates 544406..544747 (+) Length 114 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag QN094_RS02615 Protein ID WP_075211199.1
Coordinates 544044..544385 (+) Length 114 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QN094_RS02580 (QN094_02580) 539195..540070 + 876 WP_284556030.1 GTPase family protein -
QN094_RS02585 (QN094_02585) 540314..541030 + 717 WP_012543038.1 WYL domain-containing protein -
QN094_RS02590 (QN094_02590) 541066..541518 + 453 WP_000734321.1 hypothetical protein -
QN094_RS02595 (QN094_02595) 541590..542063 + 474 WP_284556031.1 hypothetical protein -
QN094_RS02600 (QN094_02600) 542183..543004 + 822 WP_284556032.1 DUF932 domain-containing protein -
QN094_RS02605 (QN094_02605) 543035..543478 + 444 WP_284556033.1 antirestriction protein -
QN094_RS02610 (QN094_02610) 543491..544033 + 543 WP_096812530.1 DNA repair protein RadC -
QN094_RS02615 (QN094_02615) 544044..544385 + 342 WP_075211199.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
QN094_RS02620 (QN094_02620) 544406..544747 + 342 WP_049123929.1 TA system toxin CbtA family protein Toxin
QN094_RS02625 (QN094_02625) 545011..546018 + 1008 WP_096812529.1 restriction endonuclease -
QN094_RS02630 (QN094_02630) 546459..547334 + 876 WP_251850016.1 HNH endonuclease -
QN094_RS02635 (QN094_02635) 547514..548524 + 1011 WP_174270262.1 LacI family DNA-binding transcriptional regulator -
QN094_RS02640 (QN094_02640) 548572..549000 - 429 WP_002437667.1 heme-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 526079..546018 19939


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-109)

Antitoxin

Antitoxin CbeA

(13-111)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12792.75 Da        Isoelectric Point: 8.4941

>T282820 WP_049123929.1 NZ_CP126339:544406-544747 [Atlantibacter hermannii]
MKTLPAITPQAATLYLSPVAVWQMLLARLLEQHYGLTLNDTPFSDETVIQEHIDAGISLADAVNFLVEKYGLVRIDRRGF
DWQEQSPYLRAVDILRARQATGLLKRNRISAAR

Download         Length: 342 bp

Antitoxin


Download         Length: 114 a.a.        Molecular weight: 12779.42 Da        Isoelectric Point: 7.0267

>AT282820 WP_075211199.1 NZ_CP126339:544044-544385 [Atlantibacter hermannii]
MKSTDSENDSFLKWGLNRNVTPCFGARLVQEGNRLHYLADRASITGKFSEAECLKLDAALPHFISQMESMLTTGEMNPRH
AHCVTLYHNGFTCEADTLGSYGYVYIAVYRTHR

Download         Length: 342 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References