Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 55753..56378 Replicon plasmid pHL21A
Accession NZ_CP126326
Organism Salmonella enterica subsp. enterica strain HL21

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QN088_RS23715 Protein ID WP_000911322.1
Coordinates 55753..56151 (-) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A8F2UQ48
Locus tag QN088_RS23720 Protein ID WP_000450263.1
Coordinates 56151..56378 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QN088_RS23695 (QN088_23695) 50909..51388 + 480 WP_284546307.1 surface exclusion protein -
QN088_RS23700 (QN088_23700) 51734..52465 + 732 WP_079975227.1 conjugal transfer complement resistance protein TraT -
QN088_RS23705 (QN088_23705) 52690..53196 + 507 WP_254880449.1 hypothetical protein -
QN088_RS23710 (QN088_23710) 53474..55744 + 2271 WP_284546308.1 type IV conjugative transfer system coupling protein TraD -
QN088_RS23715 (QN088_23715) 55753..56151 - 399 WP_000911322.1 type II toxin-antitoxin system VapC family toxin Toxin
QN088_RS23720 (QN088_23720) 56151..56378 - 228 WP_000450263.1 toxin-antitoxin system antitoxin VapB Antitoxin

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..90249 90249


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-125)

Antitoxin

SpoVT-AbrB domain

(7-51)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14887.13 Da        Isoelectric Point: 8.5264

>T282787 WP_000911322.1 NZ_CP126326:c56151-55753 [Salmonella enterica subsp. enterica]
MLKFMLDTNICIFTIKNKPASVRERFNLNQGRMCISSVTLMELIYGAEKSQMPERNLAVIEGFVSRLDVLDYDTPAATHT
GQIRAELARQGRPVGPFDQMIAGHARSRGLIVVTNNTREFERVGGLRTEDWS

Download         Length: 399 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8532.53 Da        Isoelectric Point: 4.7513

>AT282787 WP_000450263.1 NZ_CP126326:c56378-56151 [Salmonella enterica subsp. enterica]
METSVFLSNRSQAVRLPKAVALPEHVKRVEVIAVGRTRIITPAGESWDEWFDGNNVSADFMDNREQPSVQERESF

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References