Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 281336..281976 Replicon plasmid unnamed
Accession NZ_CP126308
Organism Bosea vestrisii strain A18/4-2

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QO058_RS30495 Protein ID WP_284173187.1
Coordinates 281590..281976 (+) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QO058_RS30490 Protein ID WP_284173185.1
Coordinates 281336..281590 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QO058_RS30470 (QO058_30470) 278362..278757 + 396 WP_284173181.1 hypothetical protein -
QO058_RS30475 (QO058_30475) 279140..279349 + 210 WP_284173182.1 cold-shock protein -
QO058_RS30480 (QO058_30480) 279391..280095 - 705 WP_284173183.1 SMC-Scp complex subunit ScpB -
QO058_RS30485 (QO058_30485) 280099..281004 - 906 WP_284173184.1 DUF1403 family protein -
QO058_RS30490 (QO058_30490) 281336..281590 + 255 WP_284173185.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
QO058_RS30495 (QO058_30495) 281590..281976 + 387 WP_284173187.1 type II toxin-antitoxin system VapC family toxin Toxin
QO058_RS30500 (QO058_30500) 281980..283068 + 1089 WP_284173188.1 site-specific integrase -
QO058_RS30505 (QO058_30505) 283089..283607 - 519 WP_284173190.1 RES family NAD+ phosphorylase -
QO058_RS30510 (QO058_30510) 283604..283993 - 390 WP_284173191.1 MbcA/ParS/Xre antitoxin family protein -
QO058_RS30515 (QO058_30515) 284171..284551 - 381 WP_284173192.1 hypothetical protein -
QO058_RS30520 (QO058_30520) 284529..284840 - 312 WP_284173193.1 WGR domain-containing protein -
QO058_RS30525 (QO058_30525) 284951..286180 - 1230 WP_284173195.1 plasmid replication protein RepC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..372254 372254


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-124)

Antitoxin

Antitoxin VapB-like

(1-83)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14095.96 Da        Isoelectric Point: 4.6251

>T282744 WP_284173187.1 NZ_CP126308:281590-281976 [Bosea vestrisii]
MVIDTSAIVAIFFNEPDAPRYRERIADDPVRLMSAATLLEAAMVIEGRFGEAGGAELDLWLHKAEVEIVAVTAEHADQAR
RAWRRYGKGRHPASLNYGDCFSYALAALTGEPLLFKGEDFAQTDIQVA

Download         Length: 387 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9375.77 Da        Isoelectric Point: 6.3656

>AT282744 WP_284173185.1 NZ_CP126308:281336-281590 [Bosea vestrisii]
MALSIKDPKTEKLARALAERTGETITVATRRAIEERLKRMASQGRKAALLEDMEAMQRRLDALPVLDPRSPDDIIGYDEN
GVPN

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References