Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 4688846..4689531 Replicon chromosome
Accession NZ_CP126307
Organism Bosea vestrisii strain A18/4-2

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QO058_RS23015 Protein ID WP_284168542.1
Coordinates 4688846..4689271 (-) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QO058_RS23020 Protein ID WP_284168543.1
Coordinates 4689268..4689531 (-) Length 88 a.a.

Genomic Context

QO058_RS22995QO058_RS23000QO058_RS23005QO058_RS23010QO058_RS23025QO058_RS23015QO058_RS23020QO058_RS23030QO058_RS23035QO058_RS23040QO058_RS23045QO058_RS23050
Location: 4684161..4685309 (1149 bp)
Type: Others
Protein ID: WP_284168538.1
Location: 4685339..4685713 (375 bp)
Type: Others
Protein ID: WP_284168539.1
Location: 4685874..4687214 (1341 bp)
Type: Others
Protein ID: WP_284168540.1
Location: 4687214..4688788 (1575 bp)
Type: Others
Protein ID: WP_284168541.1
Location: 4689699..4691009 (1311 bp)
Type: Others
Protein ID: WP_284168544.1
Location: 4688846..4689271 (426 bp)
Type: Toxin
Protein ID: WP_284168542.1
Location: 4689268..4689531 (264 bp)
Type: Antitoxin
Protein ID: WP_284168543.1
Location: 4691108..4691590 (483 bp)
Type: Others
Protein ID: WP_284173002.1
Location: 4691599..4692153 (555 bp)
Type: Others
Protein ID: WP_284168545.1
Location: 4692279..4692506 (228 bp)
Type: Others
Protein ID: WP_057187825.1
Location: 4692568..4693314 (747 bp)
Type: Others
Protein ID: WP_126113486.1
Location: 4693388..4693738 (351 bp)
Type: Others
Protein ID: WP_284168546.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
QO058_RS22995 (QO058_22995)4684161..4685309+1149WP_284168538.1glycine cleavage system aminomethyltransferase GcvT-
QO058_RS23000 (QO058_23000)4685339..4685713+375WP_284168539.1glycine cleavage system protein GcvH-
QO058_RS23005 (QO058_23005)4685874..4687214+1341WP_284168540.1aminomethyl-transferring glycine dehydrogenase subunit GcvPA-
QO058_RS23010 (QO058_23010)4687214..4688788+1575WP_284168541.1aminomethyl-transferring glycine dehydrogenase subunit GcvPB-
QO058_RS23015 (QO058_23015)4688846..4689271-426WP_284168542.1PIN domain-containing proteinToxin
QO058_RS23020 (QO058_23020)4689268..4689531-264WP_284168543.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
QO058_RS23025 (QO058_23025)4689699..4691009+1311WP_284168544.1L,D-transpeptidase family protein-
QO058_RS23030 (QO058_23030)4691108..4691590-483WP_284173002.1ATP F0F1 synthase subunit B-
QO058_RS23035 (QO058_23035)4691599..4692153-555WP_284168545.1F0F1 ATP synthase subunit B-
QO058_RS23040 (QO058_23040)4692279..4692506-228WP_057187825.1F0F1 ATP synthase subunit C-
QO058_RS23045 (QO058_23045)4692568..4693314-747WP_126113486.1F0F1 ATP synthase subunit A-
QO058_RS23050 (QO058_23050)4693388..4693738-351WP_284168546.1AtpZ/AtpI family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-123)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(7-70)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15620.96 Da        Isoelectric Point: 5.7529

>T282742 WP_284168542.1 NZ_CP126307:c4689271-4688846 [Bosea vestrisii]
VRILLDTNVISEPQKPQPSAAVERFIRDTPEEGLFLSIITIAELYRSVAFMTEGRRRIRLSEWVTAELPERFGDRLLPIT
TSIAALWGDVMAQSRRDGLNMSIMDGFLAATAAAHGLAIATRNVRHFTGLGLTVIDPWGES

Download         Length: 426 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9684.02 Da        Isoelectric Point: 10.0118

>AT282742 WP_284168543.1 NZ_CP126307:c4689531-4689268 [Bosea vestrisii]
MTSASKTSWSVANAKARFSELIDKAKSEGPQTVTRNGKPTVMLVSVEEWEKRTAPKGTLLEFLQNSPLRGADLDLRRLAD
QPRDIEL

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References