Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 4688846..4689531 Replicon chromosome
Accession NZ_CP126307
Organism Bosea vestrisii strain A18/4-2

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QO058_RS23015 Protein ID WP_284168542.1
Coordinates 4688846..4689271 (-) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QO058_RS23020 Protein ID WP_284168543.1
Coordinates 4689268..4689531 (-) Length 88 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QO058_RS22995 (QO058_22995) 4684161..4685309 + 1149 WP_284168538.1 glycine cleavage system aminomethyltransferase GcvT -
QO058_RS23000 (QO058_23000) 4685339..4685713 + 375 WP_284168539.1 glycine cleavage system protein GcvH -
QO058_RS23005 (QO058_23005) 4685874..4687214 + 1341 WP_284168540.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPA -
QO058_RS23010 (QO058_23010) 4687214..4688788 + 1575 WP_284168541.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPB -
QO058_RS23015 (QO058_23015) 4688846..4689271 - 426 WP_284168542.1 PIN domain-containing protein Toxin
QO058_RS23020 (QO058_23020) 4689268..4689531 - 264 WP_284168543.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QO058_RS23025 (QO058_23025) 4689699..4691009 + 1311 WP_284168544.1 L,D-transpeptidase family protein -
QO058_RS23030 (QO058_23030) 4691108..4691590 - 483 WP_284173002.1 ATP F0F1 synthase subunit B -
QO058_RS23035 (QO058_23035) 4691599..4692153 - 555 WP_284168545.1 F0F1 ATP synthase subunit B -
QO058_RS23040 (QO058_23040) 4692279..4692506 - 228 WP_057187825.1 F0F1 ATP synthase subunit C -
QO058_RS23045 (QO058_23045) 4692568..4693314 - 747 WP_126113486.1 F0F1 ATP synthase subunit A -
QO058_RS23050 (QO058_23050) 4693388..4693738 - 351 WP_284168546.1 AtpZ/AtpI family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-123)

Antitoxin

(7-70)


Sequences


Toxin        


Download         Length: 142 a.a.        Molecular weight: 15620.96 Da        Isoelectric Point: 5.7529

>T282742 WP_284168542.1 NZ_CP126307:c4689271-4688846 [Bosea vestrisii]
VRILLDTNVISEPQKPQPSAAVERFIRDTPEEGLFLSIITIAELYRSVAFMTEGRRRIRLSEWVTAELPERFGDRLLPIT
TSIAALWGDVMAQSRRDGLNMSIMDGFLAATAAAHGLAIATRNVRHFTGLGLTVIDPWGES

Download         Length: 426 bp


Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9684.02 Da        Isoelectric Point: 10.0118

>AT282742 WP_284168543.1 NZ_CP126307:c4689531-4689268 [Bosea vestrisii]
MTSASKTSWSVANAKARFSELIDKAKSEGPQTVTRNGKPTVMLVSVEEWEKRTAPKGTLLEFLQNSPLRGADLDLRRLAD
QPRDIEL

Download         Length: 264 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References