Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 4579334..4579910 Replicon chromosome
Accession NZ_CP126307
Organism Bosea vestrisii strain A18/4-2

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag QO058_RS22505 Protein ID WP_284172995.1
Coordinates 4579620..4579910 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag QO058_RS22500 Protein ID WP_284168451.1
Coordinates 4579334..4579618 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QO058_RS22465 (QO058_22465) 4574495..4575127 + 633 WP_284168444.1 molybdenum cofactor guanylyltransferase MobA -
QO058_RS22470 (QO058_22470) 4575198..4575320 + 123 WP_284168445.1 hypothetical protein -
QO058_RS22475 (QO058_22475) 4575331..4575732 - 402 WP_284168446.1 SRPBCC family protein -
QO058_RS22480 (QO058_22480) 4576160..4576381 + 222 WP_284168447.1 hypothetical protein -
QO058_RS22485 (QO058_22485) 4576386..4577519 - 1134 WP_284168448.1 Mrp/NBP35 family ATP-binding protein -
QO058_RS22490 (QO058_22490) 4577548..4577778 - 231 WP_284168449.1 sulfurtransferase TusA family protein -
QO058_RS22495 (QO058_22495) 4578054..4579325 + 1272 WP_284168450.1 c-type cytochrome -
QO058_RS22500 (QO058_22500) 4579334..4579618 - 285 WP_284168451.1 putative addiction module antidote protein Antitoxin
QO058_RS22505 (QO058_22505) 4579620..4579910 - 291 WP_284172995.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QO058_RS22510 (QO058_22510) 4579946..4581985 - 2040 WP_284168452.1 4Fe-4S binding protein -
QO058_RS22515 (QO058_22515) 4582094..4582837 + 744 WP_284168453.1 biotin/lipoate--protein ligase family protein -
QO058_RS22520 (QO058_22520) 4582834..4583388 + 555 WP_284168454.1 DUF6505 family protein -
QO058_RS22525 (QO058_22525) 4583385..4584395 + 1011 WP_284168455.1 DUF6352 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-95)

Antitoxin

Uncharacterized protein HI1420

(5-89)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10866.54 Da        Isoelectric Point: 9.5212

>T282741 WP_284172995.1 NZ_CP126307:c4579910-4579620 [Bosea vestrisii]
IPELRQTAVFSTWLEDLRDNAAKARILVRLRRLELGNPGDVKPVGEGMSEMRVDYGPGYRVYFVQRGKELIILLCGGDKR
TQANDIARAKQMAAEY

Download         Length: 291 bp

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10067.34 Da        Isoelectric Point: 4.4354

>AT282741 WP_284168451.1 NZ_CP126307:c4579618-4579334 [Bosea vestrisii]
MADETRPFDIQNHLATQDEQVAYLEAALEDGDPAFIAVALGDIARARGVTTFAEESGISRETIYKAFRAGGNPTLETLSK
ATRALGMKLTLVPA

Download         Length: 285 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References