Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 1657148..1657707 Replicon chromosome
Accession NZ_CP126307
Organism Bosea vestrisii strain A18/4-2

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QO058_RS08230 Protein ID WP_284171545.1
Coordinates 1657148..1657513 (-) Length 122 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QO058_RS08235 Protein ID WP_284171546.1
Coordinates 1657510..1657707 (-) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QO058_RS08210 (QO058_08210) 1652249..1652815 - 567 WP_284171541.1 dihydrofolate reductase family protein -
QO058_RS08215 (QO058_08215) 1653120..1654412 + 1293 WP_284171542.1 adenylosuccinate synthase -
QO058_RS08220 (QO058_08220) 1654444..1655667 + 1224 WP_284171543.1 histidine kinase -
QO058_RS08225 (QO058_08225) 1655600..1657138 - 1539 WP_284171544.1 hypothetical protein -
QO058_RS08230 (QO058_08230) 1657148..1657513 - 366 WP_284171545.1 PIN domain-containing protein Toxin
QO058_RS08235 (QO058_08235) 1657510..1657707 - 198 WP_284171546.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
QO058_RS08240 (QO058_08240) 1657786..1659408 - 1623 WP_284171547.1 peptide chain release factor 3 -
QO058_RS08245 (QO058_08245) 1659585..1661267 + 1683 WP_284171548.1 HAMP domain-containing methyl-accepting chemotaxis protein -
QO058_RS08250 (QO058_08250) 1661274..1662035 - 762 WP_126115780.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-110)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-45)


Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 12946.03 Da        Isoelectric Point: 6.6055

>T282739 WP_284171545.1 NZ_CP126307:c1657513-1657148 [Bosea vestrisii]
VILLDASVWIDHLRRGEPRLIGMLSEGDILIHPFVTAEVALGSIARRSTVIAVLDALPQAPVATHGEVMRLIAHEHLHGL
GIGYVDAHLLASARLADAGLWSRDRRLLAAAERLGVAAEAT

Download         Length: 366 bp

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7181.20 Da        Isoelectric Point: 10.1987

>AT282739 WP_284171546.1 NZ_CP126307:c1657707-1657510 [Bosea vestrisii]
MRTTVTLDDELIEKAQFYTGITERSVLLREALTALIQREAARRAIKLGGSDPDATAAPRRRQPAA

Download         Length: 198 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References