Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 1241385..1242016 Replicon chromosome
Accession NZ_CP126307
Organism Bosea vestrisii strain A18/4-2

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QO058_RS06065 Protein ID WP_284171047.1
Coordinates 1241630..1242016 (+) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QO058_RS06060 Protein ID WP_284171046.1
Coordinates 1241385..1241633 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QO058_RS06050 (QO058_06050) 1239266..1240177 - 912 WP_284171043.1 methylenetetrahydrofolate reductase [NAD(P)H] -
QO058_RS06055 (QO058_06055) 1240177..1241190 - 1014 WP_284171045.1 metalloregulator ArsR/SmtB family transcription factor -
QO058_RS06060 (QO058_06060) 1241385..1241633 + 249 WP_284171046.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
QO058_RS06065 (QO058_06065) 1241630..1242016 + 387 WP_284171047.1 type II toxin-antitoxin system VapC family toxin Toxin
QO058_RS06070 (QO058_06070) 1242029..1243459 - 1431 WP_284171049.1 PLP-dependent aminotransferase family protein -
QO058_RS06075 (QO058_06075) 1243544..1244407 + 864 WP_284171051.1 DMT family transporter -
QO058_RS06080 (QO058_06080) 1244499..1245131 - 633 WP_284171052.1 MOSC domain-containing protein -
QO058_RS06085 (QO058_06085) 1245145..1245348 - 204 WP_057190882.1 cold-shock protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-124)

Antitoxin

Antitoxin VapB-like

(1-81)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 13969.89 Da        Isoelectric Point: 5.5960

>T282738 WP_284171047.1 NZ_CP126307:1241630-1242016 [Bosea vestrisii]
MIVDTSALVAILYREPEAEAFVKRIHAAETSRISVANYVELSMVVEHQLGPEGMRQAEAFFRRAGIIIEPVSVDHGDLAR
QAFLDFGKGRHRAGLNFGDCFAYALAKASGEPLLFKGNDFSQTDIAAA

Download         Length: 387 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9234.44 Da        Isoelectric Point: 7.4029

>AT282738 WP_284171046.1 NZ_CP126307:1241385-1241633 [Bosea vestrisii]
MSLSIKDPEAHRLAQAISHATGESMTRVVTEALRERWNKIERQKGRASVEELLQIAERAAGHVKRPYADHADLLYDESGI
PK

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References