282733

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 1220699..1221616 Replicon chromosome
Accession NZ_CP126226
Organism Bacillus velezensis strain B31

Toxin (Protein)


Gene name spoIISA Uniprot ID I2HQ15
Locus tag QNM98_RS06490 Protein ID WP_007407256.1
Coordinates 1220870..1221616 (-) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID I2HQ14
Locus tag QNM98_RS06485 Protein ID WP_003154807.1
Coordinates 1220699..1220869 (-) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QNM98_RS06450 (QNM98_06450) 1215922..1217553 + 1632 WP_015417294.1 pyocin knob domain-containing protein -
QNM98_RS06455 (QNM98_06455) 1217566..1217937 + 372 WP_015417295.1 XkdW family protein -
QNM98_RS06460 (QNM98_06460) 1217942..1218139 + 198 WP_012117366.1 XkdX family protein -
QNM98_RS06465 (QNM98_06465) 1218196..1218957 + 762 WP_031378811.1 hypothetical protein -
QNM98_RS06470 (QNM98_06470) 1219009..1219272 + 264 WP_031378810.1 hemolysin XhlA family protein -
QNM98_RS06475 (QNM98_06475) 1219286..1219549 + 264 WP_003154813.1 phage holin -
QNM98_RS06480 (QNM98_06480) 1219563..1220441 + 879 WP_007407257.1 N-acetylmuramoyl-L-alanine amidase -
QNM98_RS06485 (QNM98_06485) 1220699..1220869 - 171 WP_003154807.1 type II toxin-antitoxin system SpoIISB family antitoxin Antitoxin
QNM98_RS06490 (QNM98_06490) 1220870..1221616 - 747 WP_007407256.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
QNM98_RS06495 (QNM98_06495) 1221721..1222719 - 999 WP_003154805.1 inorganic phosphate transporter -
QNM98_RS06500 (QNM98_06500) 1222732..1223349 - 618 WP_003154804.1 DUF47 domain-containing protein -
QNM98_RS06505 (QNM98_06505) 1223635..1224951 - 1317 WP_007610842.1 amino acid permease -
QNM98_RS06510 (QNM98_06510) 1225274..1226224 + 951 WP_043867021.1 ring-cleaving dioxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-239)

Antitoxin

Antitoxin SpoIISB

(1-56)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29077.57 Da        Isoelectric Point: 4.7755

>T282733 WP_007407256.1 NZ_CP126226:c1221616-1220870 [Bacillus velezensis]
MLLFFQIMVWTMAAALILYVYASWRYEAKVKEKMFAIRKTWYLLFVLGSMVYWTYDPESLFAAWRQYLIVAVCFALIDAF
IFLSAYIKKLAGNELETDTREILEENNEMLHSYLEKLKTYQYLLKNEPIHVYYGSTEAYAEGISRLLAAYAEKMNVTASL
CDYSAQSDKDRLTEHMPDAADVQSRLNRKDVYYDQKGRLVLIPFTVQNRHYVIKLTSENLLTEFDYLLFTSLTSIYDLML
PIEEEGDG

Download         Length: 747 bp

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6676.74 Da        Isoelectric Point: 10.9273

>AT282733 WP_003154807.1 NZ_CP126226:c1220869-1220699 [Bacillus velezensis]
MEQAFQNGQPEQRAKPFKMFKKRSMTSIASYQVSPHTARIFKENERLIDKYKQKKA

Download         Length: 171 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB I2HQ15

Antitoxin

Source ID Structure
AlphaFold DB I2HQ14

References