Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 3721910..3722527 Replicon chromosome
Accession NZ_CP126169
Organism Rahnella bonaserana strain L46

Toxin (Protein)


Gene name Hha Uniprot ID H8NYI7
Locus tag QNM34_RS17150 Protein ID WP_013576617.1
Coordinates 3722324..3722527 (+) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID -
Locus tag QNM34_RS17145 Protein ID WP_104923047.1
Coordinates 3721910..3722278 (+) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QNM34_RS17115 (QNM34_17115) 3717902..3718156 + 255 WP_217174193.1 type B 50S ribosomal protein L31 -
QNM34_RS17120 (QNM34_17120) 3718177..3718317 + 141 WP_095924976.1 type B 50S ribosomal protein L36 -
QNM34_RS17125 (QNM34_17125) 3718445..3719323 - 879 WP_217174194.1 metal ABC transporter substrate-binding protein -
QNM34_RS17130 (QNM34_17130) 3719367..3720224 - 858 WP_112287526.1 metal ABC transporter permease -
QNM34_RS17135 (QNM34_17135) 3720221..3720982 - 762 WP_217174195.1 ABC transporter ATP-binding protein -
QNM34_RS17140 (QNM34_17140) 3721334..3721687 + 354 WP_284003171.1 hypothetical protein -
QNM34_RS17145 (QNM34_17145) 3721910..3722278 + 369 WP_104923047.1 Hha toxicity modulator TomB Antitoxin
QNM34_RS17150 (QNM34_17150) 3722324..3722527 + 204 WP_013576617.1 HHA domain-containing protein Toxin
QNM34_RS17155 (QNM34_17155) 3722610..3723560 - 951 WP_284006264.1 LysR family transcriptional regulator -
QNM34_RS17160 (QNM34_17160) 3723697..3725484 + 1788 WP_284003180.1 adenine deaminase C-terminal domain-containing protein -
QNM34_RS17165 (QNM34_17165) 3725560..3726909 + 1350 WP_217174199.1 NCS2 family permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-118)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8114.45 Da        Isoelectric Point: 6.9764

>T282731 WP_013576617.1 NZ_CP126169:3722324-3722527 [Rahnella bonaserana]
MNKIDYLMRLRKCTTIDTLERVIEKNKYELSDDELELFYSAADHRLAELTMNKLYDKIPVSVWKFVR

Download         Length: 204 bp

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 14378.15 Da        Isoelectric Point: 4.7281

>AT282731 WP_104923047.1 NZ_CP126169:3721910-3722278 [Rahnella bonaserana]
MDEYSPKRHDIAQLRYLNEMLYDEGIATLGDSHHGWVNDPTSAVNLQLNELIEHIASFVMSFKIKYPDDTHLSDLVEEYL
DDTYTLFSNYGINDSDLRQWQKTKKRLFRMFSGDYICTLMKT

Download         Length: 369 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB H8NYI7

Antitoxin

Source ID Structure

References