Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-HipB
Location 2055893..2057470 Replicon chromosome
Accession NZ_CP126169
Organism Rahnella bonaserana strain L46

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag QNM34_RS09300 Protein ID WP_217173021.1
Coordinates 2056175..2057470 (+) Length 432 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag QNM34_RS09295 Protein ID WP_274388747.1
Coordinates 2055893..2056171 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QNM34_RS09275 (QNM34_09275) 2051193..2052065 + 873 WP_217173017.1 fumarylacetoacetate hydrolase family protein -
QNM34_RS09280 (QNM34_09280) 2052072..2053472 - 1401 WP_284006236.1 PTS transporter subunit EIIC -
QNM34_RS09285 (QNM34_09285) 2053797..2054996 + 1200 WP_284006014.1 enolase C-terminal domain-like protein -
QNM34_RS09290 (QNM34_09290) 2055002..2055712 - 711 WP_217173019.1 GntR family transcriptional regulator -
QNM34_RS09295 (QNM34_09295) 2055893..2056171 + 279 WP_274388747.1 helix-turn-helix domain-containing protein Antitoxin
QNM34_RS09300 (QNM34_09300) 2056175..2057470 + 1296 WP_217173021.1 type II toxin-antitoxin system HipA family toxin Toxin
QNM34_RS09305 (QNM34_09305) 2057534..2060023 - 2490 WP_284006015.1 membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family -
QNM34_RS09310 (QNM34_09310) 2060403..2061290 - 888 WP_217173023.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(149-398)

Antitoxin

Cro/C1-type helix-turn-helix domain

(19-73)


Sequences

Toxin        


Download         Length: 432 a.a.        Molecular weight: 48222.49 Da        Isoelectric Point: 6.9718

>T282725 WP_217173021.1 NZ_CP126169:2056175-2057470 [Rahnella bonaserana]
MDKLTLALNGIAVGTLEKGGSGEMSFVYHQSWLDRPGARAISLSLPLQADKFRGAVVYNFFDNLLPDNEQIRSRIQARFQ
IPTKQPFDLLSRIGGDCVGAIQLYPEGDQVAPVTEIHARPLDEKDVEQLLQGYKDAPLGMEADIEDFRISLAGAQEKTAL
LWYRDQWHRPQGSTPTSHILKLPIGYIANNGIDLSESVENEWLCLKIAEKFGFPVARSEIASFGAQKVLVVERFDRRWSQ
DGSWLMRIPQEDFCQALGVAPALKYESDGGPGIARAMKLLLGSQRAGADRDMFFKSQILFWMLAAIDGHAKNFSVYIEPG
SAYRMTPLYDVMSAFPLMNPQGIPAKKAKMAMAVLGKNRHFHWDRILPRHFVTTAQRVEYSKENVAVMMTEMKEKTEQVI
ADVEAIIPANFPVKISDAIFAGLRHQAARLP

Download         Length: 1296 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10628.05 Da        Isoelectric Point: 9.7246

>AT282725 WP_274388747.1 NZ_CP126169:2055893-2056171 [Rahnella bonaserana]
MRLSAREDNMNITSAKMLANALRNERKKRKLSQSKTAETIGLKQSTVSEFENYPDGTRLETLFKLLAALDLELQITPRDS
NPKEKTSWDQEW

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References