282699

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 123928..124540 Replicon plasmid p6
Accession NZ_CP126151
Organism Sagittula sp. MA-2

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QNI11_RS26970 Protein ID WP_088716084.1
Coordinates 124145..124540 (+) Length 132 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QNI11_RS26965 Protein ID WP_088716083.1
Coordinates 123928..124155 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QNI11_RS26950 (QNI11_26950) 120185..121396 - 1212 WP_283984049.1 plasmid replication protein RepC -
QNI11_RS26955 (QNI11_26955) 121609..122541 - 933 WP_283984050.1 plasmid partitioning protein RepB -
QNI11_RS26960 (QNI11_26960) 122525..123718 - 1194 WP_088716082.1 plasmid partitioning protein RepA -
QNI11_RS26965 (QNI11_26965) 123928..124155 + 228 WP_088716083.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
QNI11_RS26970 (QNI11_26970) 124145..124540 + 396 WP_088716084.1 PIN domain-containing protein Toxin
QNI11_RS26975 (QNI11_26975) 124619..125503 - 885 WP_283984051.1 recombinase family protein -
QNI11_RS26980 (QNI11_26980) 126051..127118 + 1068 WP_283984052.1 hypothetical protein -
QNI11_RS26985 (QNI11_26985) 127756..128343 - 588 WP_038070177.1 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..162034 162034
- flank IS/Tn - - 127756..128343 587


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-113)

Antitoxin

SpoVT-AbrB domain

(5-45)


Sequences

Toxin        


Download         Length: 132 a.a.        Molecular weight: 14244.23 Da        Isoelectric Point: 4.1653

>T282699 WP_088716084.1 NZ_CP126151:124145-124540 [Sagittula sp. MA-2]
MSAEFADTNVVLYLLDDGPKADRAEVILGQGPRISVQVLNETLVNCRRKAGLSWEEAAAFLEGVRSLCPVEDLTVQTHDV
GRALAERYGFSIYDAMIVASALVAGCTTLWSEDMQDGLLVEGQLRIVNPFA

Download         Length: 396 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8551.79 Da        Isoelectric Point: 11.0482

>AT282699 WP_088716083.1 NZ_CP126151:123928-124155 [Sagittula sp. MA-2]
MQVAKWGNSLAVRLPAELVRELGLKEGDQIDLVKDDGRVRVRRLARADEVLTGLRRFRGKLSSAERLSRDDAHER

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References