Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 16467..17028 Replicon plasmid p4
Accession NZ_CP126149
Organism Sagittula sp. MA-2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QNI11_RS25260 Protein ID WP_036766824.1
Coordinates 16753..17028 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A940ECX6
Locus tag QNI11_RS25255 Protein ID WP_027246657.1
Coordinates 16467..16766 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QNI11_RS25230 (QNI11_25230) 12219..12428 + 210 WP_283983982.1 DUF6330 family protein -
QNI11_RS25235 (QNI11_25235) 12516..12905 + 390 WP_283983983.1 DUF3768 domain-containing protein -
QNI11_RS25240 (QNI11_25240) 13056..15038 + 1983 WP_283983984.1 ParB/RepB/Spo0J family partition protein -
QNI11_RS25245 (QNI11_25245) 15113..15706 + 594 WP_009503761.1 hypothetical protein -
QNI11_RS25250 (QNI11_25250) 15706..16362 + 657 WP_283983985.1 hypothetical protein -
QNI11_RS25255 (QNI11_25255) 16467..16766 + 300 WP_027246657.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
QNI11_RS25260 (QNI11_25260) 16753..17028 + 276 WP_036766824.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
QNI11_RS25265 (QNI11_25265) 17136..19310 + 2175 Protein_19 strawberry notch family protein -
QNI11_RS25270 (QNI11_25270) 19434..20438 - 1005 WP_088626524.1 tyrosine-type recombinase/integrase -
QNI11_RS25275 (QNI11_25275) 20438..21790 - 1353 WP_100931402.1 tyrosine-type recombinase/integrase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..77613 77613


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-54)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10411.96 Da        Isoelectric Point: 5.5881

>T282697 WP_036766824.1 NZ_CP126149:16753-17028 [Sagittula sp. MA-2]
MPNLEWKATAIADLLAIIDYISDDNPDAAQVLKDEIEHKTSRLPKHPQMYRAGRVDGTREMVVRPNYIVVYAESPEMVTI
LRVLHAAQQWP

Download         Length: 276 bp

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10520.99 Da        Isoelectric Point: 5.6448

>AT282697 WP_027246657.1 NZ_CP126149:16467-16766 [Sagittula sp. MA-2]
MPAQTSMLHVRVDDQLKAQASDALAGVGLTLSDAVRILLTRVAAEGGLPAGLTADPDAYDAWFRAKVQEALDDPRPTTPH
TKVMQDAQALIDGKRLAKS

Download         Length: 300 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References