Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazF-pemI/MazF(toxin)
Location 240358..240994 Replicon chromosome
Accession NZ_CP126144
Organism Neobacillus sp. 114

Toxin (Protein)


Gene name mazF Uniprot ID K6DRS5
Locus tag QNN06_RS01285 Protein ID WP_007083556.1
Coordinates 240644..240994 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag QNN06_RS01280 Protein ID WP_213120931.1
Coordinates 240358..240639 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QNN06_RS01260 236669..237259 - 591 WP_213120935.1 rhomboid family intramembrane serine protease -
QNN06_RS01265 237350..237703 + 354 WP_284036783.1 holo-ACP synthase -
QNN06_RS01270 237870..238883 + 1014 WP_213148132.1 outer membrane lipoprotein carrier protein LolA -
QNN06_RS01275 239016..240173 + 1158 WP_284036784.1 alanine racemase -
QNN06_RS01280 240358..240639 + 282 WP_213120931.1 CopG family ribbon-helix-helix protein Antitoxin
QNN06_RS01285 240644..240994 + 351 WP_007083556.1 type II toxin-antitoxin system endoribonuclease NdoA Toxin
QNN06_RS01290 241737..243911 + 2175 WP_284036785.1 Tex family protein -
QNN06_RS01295 243929..244039 - 111 WP_213120929.1 cortex morphogenetic protein CmpA -
QNN06_RS01300 244134..244610 + 477 WP_284036786.1 SprT family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(4-110)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13006.03 Da        Isoelectric Point: 4.8998

>T282696 WP_007083556.1 NZ_CP126144:240644-240994 [Neobacillus sp. 114]
MIVKRGDVYFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDAKRYGFERDSVILLEQI
RTIDKQRLTDKITHLDDEMMEKVDEALQVSLGLIEF

Download         Length: 351 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10839.34 Da        Isoelectric Point: 7.2029

>AT282696 WP_213120931.1 NZ_CP126144:240358-240639 [Neobacillus sp. 114]
VSESSATTEILVKLPQHLLTELDGFVKQENVNRSEFIYQATKMYLRERKTRQIRESMRRGYMEMAKINLRIASEAFQAEY
EAEHTVERLVSGG

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB K6DRS5

Antitoxin

Source ID Structure

References