Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 825017..825677 Replicon chromosome
Accession NZ_CP126140
Organism Salmonella enterica subsp. enterica serovar Enteritidis strain DSE06

Toxin (Protein)


Gene name cptA Uniprot ID Q57K70
Locus tag QNM21_RS03965 Protein ID WP_000244756.1
Coordinates 825264..825677 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag QNM21_RS03960 Protein ID WP_000351186.1
Coordinates 825017..825283 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QNM21_RS03940 (820946) 820946..822379 - 1434 WP_001230141.1 6-phospho-beta-glucosidase BglA -
QNM21_RS03945 (822537) 822537..822848 + 312 WP_001182976.1 N(4)-acetylcytidine aminohydrolase -
QNM21_RS03950 (823012) 823012..823671 + 660 WP_000250289.1 hemolysin III family protein -
QNM21_RS03955 (823787) 823787..824767 - 981 WP_000874176.1 tRNA-modifying protein YgfZ -
QNM21_RS03960 (825017) 825017..825283 + 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
QNM21_RS03965 (825264) 825264..825677 + 414 WP_000244756.1 protein YgfX Toxin
QNM21_RS03970 (825730) 825730..826251 - 522 WP_001055885.1 flavodoxin FldB -
QNM21_RS03975 (826364) 826364..827260 + 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
QNM21_RS03980 (827284) 827284..827997 + 714 WP_000745614.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
QNM21_RS03985 (828003) 828003..829736 + 1734 WP_000813389.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16183.15 Da        Isoelectric Point: 10.7537

>T282677 WP_000244756.1 NZ_CP126140:825264-825677 [Salmonella enterica subsp. enterica serovar Enteritidis]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLRPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT282677 WP_000351186.1 NZ_CP126140:825017-825283 [Salmonella enterica subsp. enterica serovar Enteritidis]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3Z1E9V5

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References