Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 22597..23222 Replicon plasmid unnamed1
Accession NZ_CP126139
Organism Salmonella enterica subsp. enterica serovar Kottbus strain DSK01

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QNM33_RS24035 Protein ID WP_000911322.1
Coordinates 22597..22995 (-) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QNM33_RS24040 Protein ID WP_000450265.1
Coordinates 22995..23222 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QNM33_RS24020 (QNM33_24020) 18788..19282 + 495 WP_010999946.1 entry exclusion protein -
QNM33_RS24025 (QNM33_24025) 19318..20049 + 732 WP_000782438.1 conjugal transfer complement resistance protein TraT -
QNM33_RS24030 (QNM33_24030) 20426..22588 + 2163 WP_000009318.1 type IV conjugative transfer system coupling protein TraD -
QNM33_RS24035 (QNM33_24035) 22597..22995 - 399 WP_000911322.1 type II toxin-antitoxin system VapC family toxin Toxin
QNM33_RS24040 (QNM33_24040) 22995..23222 - 228 WP_000450265.1 toxin-antitoxin system antitoxin VapB Antitoxin

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - rck / pefD / pefC / pefA / pefB / fdeC / spvC / spvB 1..93855 93855


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-125)

Antitoxin

SpoVT-AbrB domain

(7-51)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14887.13 Da        Isoelectric Point: 8.5264

>T282672 WP_000911322.1 NZ_CP126139:c22995-22597 [Salmonella enterica subsp. enterica serovar Kottbus]
MLKFMLDTNICIFTIKNKPASVRERFNLNQGRMCISSVTLMELIYGAEKSQMPERNLAVIEGFVSRLDVLDYDTPAATHT
GQIRAELARQGRPVGPFDQMIAGHARSRGLIVVTNNTREFERVGGLRTEDWS

Download         Length: 399 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8509.49 Da        Isoelectric Point: 4.5358

>AT282672 WP_000450265.1 NZ_CP126139:c23222-22995 [Salmonella enterica subsp. enterica serovar Kottbus]
METSVFLSNRSQAVRLPKAVALPENVKRVEVIAVGRTRIITPAGESWDEWFDGNNVSADFMDNREQPSVQERESF

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References