Detailed information of TA system TA282647

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /Acetyltransf_4(toxin)
• Location: 4018346..4019747
• Replicon: chromosome
• Accession: NZ_CP126126
• Organism: Pseudomonas sp. SO81

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: OH686_RS19090
• Protein ID: WP_289534508.1
• Coordinates: 4018346..4018915 (+)
• Length: 190 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: OH686_RS19095
• Protein ID: WP_289534509.1
• Coordinates: 4018920..4019747 (+)
• Length: 276 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OH686_RS19080 (OH686_19590)	4013893..4014591	-	699	WP_289534504.1	pirin family protein	-
OH686_RS19085 (OH686_19595)	4014712..4018182	-	3471	WP_289534506.1	PAS domain-containing hybrid sensor histidine kinase/response regulator	-
OH686_RS19090 (OH686_19605)	4018346..4018915	+	570	WP_289534508.1	GNAT family protein	Toxin
OH686_RS19095 (OH686_19610)	4018920..4019747	+	828	WP_289534509.1	AraC family transcriptional regulator	Antitoxin
OH686_RS19100 (OH686_19615)	4019819..4020529	+	711	WP_289534510.1	AzlC family ABC transporter permease	-
OH686_RS19105 (OH686_19620)	4020529..4020858	+	330	WP_137971419.1	AzlD domain-containing protein	-
OH686_RS19110 (OH686_19625)	4020963..4023089	+	2127	WP_289534512.1	TonB-dependent siderophore receptor	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (14-146)

Antitoxin

• DNA binding HTH domain, AraC-type (193-270)

Sequences

Toxin

Protein

• Length: 190 a.a.
• Molecular weight: 21387.34 Da
• Isoelectric Point: 8.5115

>T282647 WP_289534508.1 NZ_CP126126:4018346-4018915 [Pseudomonas sp. SO81]
MFKPQPVALQQGALRLDPLSESDLPGLLELAEANRESQQYMSGTTRPDWYRNALAEQREGREVVFAIRLAGELVGTTSFF
DFNPVLPAAEIGATWLDARQHGTGLNRMIKYLMLRHAFEEWQLVRVQLKTAASNLRSQRAIEKLGAQREGLLRNHRRLAD
GRLDHTVMYSITDSEWPQVKAGLEARFGA

Nucleotide

• Length: 570 bp

Antitoxin

Protein

• Length: 276 a.a.
• Molecular weight: 30560.74 Da
• Isoelectric Point: 8.5385

>AT282647 WP_289534509.1 NZ_CP126126:4018920-4019747 [Pseudomonas sp. SO81]
MAGGERTRFWESQALTGVELLHARYIEQRFAPHVHEGFVFTVIEGGAQRFRHRGSDHLAPVGSMVLINPDEVHTGSKAHE
QGWWYRGFYPAPAQVQGVLAELGLAGGGMPSFGVSVLQDLDLHQAFGQLHRLLDSDADALQQQTAWREAILLLFQRHARI
SQPAEPGREPRAVALAKELLAARLGEPPSLEELAALVNLSPFHFARVFRRATGLPPHAWLKQRRLEQARALLRSGCAPLQ
VALQLGFSDQSHLSRQFKQSYGVSPGEYRRACADF

Nucleotide

• Length: 828 bp