282639

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazF-pemI/MazF(toxin)
Location 402094..402730 Replicon chromosome
Accession NZ_CP126110
Organism Neobacillus sp. WH10

Toxin (Protein)


Gene name mazF Uniprot ID K6DRS5
Locus tag QNH20_RS02020 Protein ID WP_007083556.1
Coordinates 402380..402730 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID A0A1S2RGM2
Locus tag QNH20_RS02015 Protein ID WP_071354167.1
Coordinates 402094..402375 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QNH20_RS01995 (QNH20_01995) 397928..398656 - 729 WP_283921282.1 rhomboid family intramembrane serine protease -
QNH20_RS02000 (QNH20_02000) 398750..399097 + 348 WP_283921283.1 holo-ACP synthase -
QNH20_RS02005 (QNH20_02005) 399523..400536 + 1014 WP_283921284.1 outer membrane lipoprotein carrier protein LolA -
QNH20_RS02010 (QNH20_02010) 400667..401830 + 1164 WP_283921285.1 alanine racemase -
QNH20_RS02015 (QNH20_02015) 402094..402375 + 282 WP_071354167.1 YlcI/YnfO family protein Antitoxin
QNH20_RS02020 (QNH20_02020) 402380..402730 + 351 WP_007083556.1 type II toxin-antitoxin system endoribonuclease NdoA Toxin
QNH20_RS02025 (QNH20_02025) 402895..405081 + 2187 WP_283921286.1 Tex family protein -
QNH20_RS02030 (QNH20_02030) 405149..405262 - 114 WP_139311313.1 cortex morphogenetic protein CmpA -
QNH20_RS02035 (QNH20_02035) 405360..405833 + 474 WP_283921287.1 SprT family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(4-110)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13006.03 Da        Isoelectric Point: 4.8998

>T282639 WP_007083556.1 NZ_CP126110:402380-402730 [Neobacillus sp. WH10]
MIVKRGDVYFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDAKRYGFERDSVILLEQI
RTIDKQRLTDKITHLDDEMMEKVDEALQVSLGLIEF

Download         Length: 351 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10836.38 Da        Isoelectric Point: 8.4664

>AT282639 WP_071354167.1 NZ_CP126110:402094-402375 [Neobacillus sp. WH10]
VSESGATTEILVKLPQHLLTELDGFVKQENVNRSEFIYQATKMYLRERKKRQIRESMRRGYMEMAKINLRIASEAFQAEY
EAEHTVERLVSGG

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB K6DRS5

Antitoxin

Source ID Structure
AlphaFold DB A0A1S2RGM2

References