Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yxiD-yxxD/-
Location 295517..296361 Replicon chromosome
Accession NZ_CP126108
Organism Cytobacillus firmus strain SQ11

Toxin (Protein)


Gene name yxiD Uniprot ID -
Locus tag QNH42_RS01650 Protein ID WP_283935295.1
Coordinates 295517..295915 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name yxxD Uniprot ID -
Locus tag QNH42_RS01655 Protein ID WP_226620340.1
Coordinates 295924..296361 (+) Length 146 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QNH42_RS01625 (QNH42_01625) 291361..291708 + 348 WP_226620345.1 glyoxalase -
QNH42_RS01630 (QNH42_01630) 291845..293029 - 1185 WP_226620344.1 DUF4317 domain-containing protein -
QNH42_RS01635 (QNH42_01635) 293281..293568 - 288 WP_226620343.1 YwqI/YxiC family protein -
QNH42_RS01640 (QNH42_01640) 293582..293941 - 360 WP_250801594.1 DUF5082 family protein -
QNH42_RS01645 (QNH42_01645) 294199..295536 + 1338 WP_283935294.1 LXG domain-containing protein -
QNH42_RS01650 (QNH42_01650) 295517..295915 + 399 WP_283935295.1 HNH endonuclease Toxin
QNH42_RS01655 (QNH42_01655) 295924..296361 + 438 WP_226620340.1 SMI1/KNR4 family protein Antitoxin
QNH42_RS01660 (QNH42_01660) 296537..296737 + 201 WP_076262170.1 hypothetical protein -
QNH42_RS01665 (QNH42_01665) 297029..298219 + 1191 WP_197245259.1 M14 family zinc carboxypeptidase -
QNH42_RS01670 (QNH42_01670) 298262..298885 - 624 WP_048010876.1 DUF421 domain-containing protein -
QNH42_RS01675 (QNH42_01675) 299065..300063 + 999 WP_048010875.1 ABC transporter substrate-binding protein -
QNH42_RS01680 (QNH42_01680) 300553..300846 + 294 WP_009336200.1 WXG100 family type VII secretion target -
QNH42_RS01685 (QNH42_01685) 300926..301165 + 240 WP_197245261.1 EsaB/YukD family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Knr4/Smi1-like domain

(16-130)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 15451.36 Da        Isoelectric Point: 10.0026

>T282637 WP_283935295.1 NZ_CP126108:295517-295915 [Cytobacillus firmus]
MRDIEAKTGRKVNKEQIDLIKEDLRNKNYEKLTPRETAKHRSKFTSSLKDKLIAEWEEKTNQKWPRYTEEVLDKNGEVAR
SIGQPYDAHHIIENNFGGPHEWWNIHPAKYPNEHQAGIHGKGAPSGKLFPRR

Download         Length: 399 bp

Antitoxin


Download         Length: 146 a.a.        Molecular weight: 16884.90 Da        Isoelectric Point: 3.7177

>AT282637 WP_226620340.1 NZ_CP126108:295924-296361 [Cytobacillus firmus]
MADFEFINELENKLYKVTNDDILKAEQRMDISLPNDLKQLYLEVGYGFIEGLSANSINRILGPGAVADIRLREGVFEFDP
DLDELFDDEDKLIFFEVNEGVYISIDLQLANNPIFYFDTQIAESLEDFFKKFLNNNEYFIDLIED

Download         Length: 438 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References