282631

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 1256708..1257625 Replicon chromosome
Accession NZ_CP126104
Organism Bacillus velezensis strain MB7_B11

Toxin (Protein)


Gene name spoIISA Uniprot ID -
Locus tag QNH19_RS06570 Protein ID WP_015239694.1
Coordinates 1256879..1257625 (-) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID I2HQ14
Locus tag QNH19_RS06565 Protein ID WP_003154807.1
Coordinates 1256708..1256878 (-) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QNH19_RS06530 (QNH19_06530) 1251933..1253564 + 1632 WP_283888200.1 pyocin knob domain-containing protein -
QNH19_RS06535 (QNH19_06535) 1253577..1253948 + 372 WP_043021266.1 XkdW family protein -
QNH19_RS06540 (QNH19_06540) 1253953..1254150 + 198 WP_007610833.1 XkdX family protein -
QNH19_RS06545 (QNH19_06545) 1254207..1254968 + 762 WP_076423976.1 phage portal protein -
QNH19_RS06550 (QNH19_06550) 1255020..1255283 + 264 WP_003154815.1 hemolysin XhlA family protein -
QNH19_RS06555 (QNH19_06555) 1255297..1255560 + 264 WP_003154813.1 phage holin -
QNH19_RS06560 (QNH19_06560) 1255574..1256452 + 879 WP_129004094.1 N-acetylmuramoyl-L-alanine amidase -
QNH19_RS06565 (QNH19_06565) 1256708..1256878 - 171 WP_003154807.1 type II toxin-antitoxin system SpoIISB family antitoxin Antitoxin
QNH19_RS06570 (QNH19_06570) 1256879..1257625 - 747 WP_015239694.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
QNH19_RS06575 (QNH19_06575) 1257730..1258728 - 999 WP_007407255.1 inorganic phosphate transporter -
QNH19_RS06580 (QNH19_06580) 1258741..1259358 - 618 WP_003154804.1 DUF47 domain-containing protein -
QNH19_RS06585 (QNH19_06585) 1259644..1260960 - 1317 WP_007610842.1 amino acid permease -
QNH19_RS06590 (QNH19_06590) 1261283..1262233 + 951 WP_012117369.1 ring-cleaving dioxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1223162..1265889 42727


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-239)

Antitoxin

Antitoxin SpoIISB

(1-56)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29135.61 Da        Isoelectric Point: 4.7003

>T282631 WP_015239694.1 NZ_CP126104:c1257625-1256879 [Bacillus velezensis]
MLLFFQIMVWTMAAALILYVYASWRYEAKVKEKMFAIRKTWYLLFVLGSMVYWTYDPESLFAEWRQYLIVAVCFALIDAF
IFLSAYIKKLAGNELETDTREILEENNEMLHSYLEKLKTYQYLLKNEPIHVYYGSTEAYAEGISRLLAAYAEKMNVTASL
CDYSAQSDKDRLTEHMPDAADVQSRLNRKDVYYDQKGRLVLIPFTVQNRHYVIKLTSENLLTEFDYLLFTSLTSIYDLML
PIEEEGDG

Download         Length: 747 bp

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6676.74 Da        Isoelectric Point: 10.9273

>AT282631 WP_003154807.1 NZ_CP126104:c1256878-1256708 [Bacillus velezensis]
MEQAFQNGQPEQRAKPFKMFKKRSMTSIASYQVSPHTARIFKENERLIDKYKQKKA

Download         Length: 171 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB I2HQ14

References