Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /SpoIISA(toxin)
Location 2355510..2356485 Replicon chromosome
Accession NZ_CP126099
Organism Bacillus wiedmannii strain LN15

Toxin (Protein)


Gene name spoIISA Uniprot ID -
Locus tag QNH45_RS12150 Protein ID WP_002007672.1
Coordinates 2355510..2356247 (+) Length 246 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag QNH45_RS12155 Protein ID WP_215563265.1
Coordinates 2356360..2356485 (+) Length 42 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QNH45_RS12125 (QNH45_12125) 2350856..2351566 + 711 WP_283885897.1 class I SAM-dependent methyltransferase -
QNH45_RS12130 (QNH45_12130) 2351686..2352093 + 408 WP_212957044.1 VOC family protein -
QNH45_RS12135 (QNH45_12135) 2352141..2353817 - 1677 WP_283885898.1 alpha-keto acid decarboxylase family protein -
QNH45_RS12140 (QNH45_12140) 2353934..2354416 + 483 WP_000191899.1 MarR family transcriptional regulator -
QNH45_RS12145 (QNH45_12145) 2354584..2355321 + 738 WP_283885899.1 2,3-diphosphoglycerate-dependent phosphoglycerate mutase -
QNH45_RS12150 (QNH45_12150) 2355510..2356247 + 738 WP_002007672.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
QNH45_RS12155 (QNH45_12155) 2356360..2356485 + 126 WP_215563265.1 D-alanyl-D-alanine carboxypeptidase Antitoxin
QNH45_RS12160 (QNH45_12160) 2356561..2356737 + 177 WP_000808010.1 stage II sporulation protein SB -
QNH45_RS12165 (QNH45_12165) 2356880..2358349 + 1470 WP_283885900.1 beta-Ala-His dipeptidase -
QNH45_RS12170 (QNH45_12170) 2358945..2359415 - 471 WP_283885902.1 DUF5065 family protein -
QNH45_RS12175 (QNH45_12175) 2359870..2360529 + 660 WP_087980446.1 CatB-related O-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(9-243)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 246 a.a.        Molecular weight: 28280.95 Da        Isoelectric Point: 8.2998

>T282617 WP_002007672.1 NZ_CP126099:2355510-2356247 [Bacillus wiedmannii]
VSSNIRIGLFILAIVFLVLVFFYWKNEELYEEKKQRIRKTWYGLFIISVTVYFMIKGIDLTLWKNLLMFTAMVIFVDIAF
ILTPNISEIWGAKFSDIGKTVQSIKRSLIASKARGEIYTTIIQNVNPAVFGTMEWHTEEEYSKSLNAFLDSYGEKIGAKI
VVFEAAKELNTNFRGIRSQFSIIVPLEHIEQLNEQKAVQVENVGIIPAKMVSDVFIVIDGKKNNLQDRDFENVYNLTIHH
SYFSK

Download         Length: 738 bp

Antitoxin


Download         Length: 42 a.a.        Molecular weight: 4970.45 Da        Isoelectric Point: 4.0338

>AT282617 WP_215563265.1 NZ_CP126099:2356360-2356485 [Bacillus wiedmannii]
MIKDYDNDFFKEDNEDTTDFSLIKGDTLKQVEELEEELKRK

Download         Length: 126 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References