282602

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazF-pemI/MazF(toxin)
Location 261145..261781 Replicon chromosome
Accession NZ_CP126093
Organism Neobacillus sp. DY30

Toxin (Protein)


Gene name mazF Uniprot ID A0A1H0EHG9
Locus tag QNH29_RS01365 Protein ID WP_034673264.1
Coordinates 261431..261781 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag QNH29_RS01360 Protein ID WP_192655130.1
Coordinates 261145..261426 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QNH29_RS01340 (QNH29_01340) 257486..258079 - 594 WP_283863103.1 rhomboid family intramembrane serine protease -
QNH29_RS01345 (QNH29_01345) 258178..258528 + 351 WP_283863104.1 holo-ACP synthase -
QNH29_RS01350 (QNH29_01350) 258657..259667 + 1011 WP_283863105.1 outer membrane lipoprotein carrier protein LolA -
QNH29_RS01355 (QNH29_01355) 259797..260960 + 1164 WP_283863106.1 alanine racemase -
QNH29_RS01360 (QNH29_01360) 261145..261426 + 282 WP_192655130.1 YlcI/YnfO family protein Antitoxin
QNH29_RS01365 (QNH29_01365) 261431..261781 + 351 WP_034673264.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
QNH29_RS01370 (QNH29_01370) 261945..264119 + 2175 WP_283863107.1 Tex family protein -
QNH29_RS01375 (QNH29_01375) 264365..264478 - 114 WP_095251326.1 cortex morphogenetic protein CmpA -
QNH29_RS01380 (QNH29_01380) 264571..265044 + 474 WP_283863108.1 SprT family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(4-110)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13034.09 Da        Isoelectric Point: 5.1961

>T282602 WP_034673264.1 NZ_CP126093:261431-261781 [Neobacillus sp. DY30]
MIVKRGDVYFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDAKRYGFERDSVILLEQI
RTIDKQRLTDKITHLDDEMMEKVDEALRVSIGLIEF

Download         Length: 351 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10753.34 Da        Isoelectric Point: 6.4751

>AT282602 WP_192655130.1 NZ_CP126093:261145-261426 [Neobacillus sp. DY30]
VSESGATTEILVKLPQHLLTELDGFVKLENVNRSEFIYQATKMYLRERKKRQLRESMRRGYMEMAMINLTIASEAFQAEF
EAEHTVERLVSGG

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1H0EHG9

Antitoxin

Source ID Structure

References