282600

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 1437108..1438027 Replicon chromosome
Accession NZ_CP126091
Organism Bacillus paralicheniformis strain CEW 1W

Toxin (Protein)


Gene name spoIISA Uniprot ID A0A6I7TYV7
Locus tag QNH18_RS07275 Protein ID WP_023856735.1
Coordinates 1437281..1438027 (-) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID A0A6I7TM13
Locus tag QNH18_RS07270 Protein ID WP_023856734.1
Coordinates 1437108..1437281 (-) Length 58 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QNH18_RS07245 (QNH18_07245) 1432533..1433630 + 1098 WP_283931643.1 mannonate dehydratase -
QNH18_RS07250 (QNH18_07250) 1433606..1434454 + 849 WP_035338918.1 SDR family oxidoreductase -
QNH18_RS07255 (QNH18_07255) 1434480..1435493 + 1014 WP_283931644.1 zinc-binding alcohol dehydrogenase family protein -
QNH18_RS07260 (QNH18_07260) 1435545..1436816 + 1272 WP_026579844.1 MFS transporter -
QNH18_RS07265 (QNH18_07265) 1436883..1437014 - 132 WP_023856733.1 hypothetical protein -
QNH18_RS07270 (QNH18_07270) 1437108..1437281 - 174 WP_023856734.1 type II toxin-antitoxin system SpoIISB family antitoxin Antitoxin
QNH18_RS07275 (QNH18_07275) 1437281..1438027 - 747 WP_023856735.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
QNH18_RS07280 (QNH18_07280) 1438137..1439135 - 999 WP_075212749.1 inorganic phosphate transporter -
QNH18_RS07285 (QNH18_07285) 1439148..1439765 - 618 WP_023856737.1 DUF47 domain-containing protein -
QNH18_RS07290 (QNH18_07290) 1440098..1441855 + 1758 WP_026579843.1 gamma-glutamyltransferase -
QNH18_RS07295 (QNH18_07295) 1441990..1442634 + 645 WP_003180888.1 YesL family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-238)

Antitoxin

Antitoxin SpoIISB

(1-57)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29421.87 Da        Isoelectric Point: 4.6015

>T282600 WP_023856735.1 NZ_CP126091:c1438027-1437281 [Bacillus paralicheniformis]
MLLFYQFLVWLIVLALALYVAAVWRFEKKLTEKTVAIRKTWYLLYVIGAVIYWTHDPQSIFTNPLHYLIVAVFFTLTDAF
IFLNAYFKKLGSSELATDTRMLLEENNDLLHTYQNRLKTFQYLLKNEPIHIYYGNIEAYAEGIEKLIKRFAEKMNISAAL
CEYNSEESKDHLLEHMENRFDVQEKLERKDVYYEENGKMVLIPFSIHDFDYVMKLTSEDLVTEFDYLLFTSLTSIYDLLL
PNEEDGDD

Download         Length: 747 bp

Antitoxin


Download         Length: 58 a.a.        Molecular weight: 6897.99 Da        Isoelectric Point: 10.8356

>AT282600 WP_023856734.1 NZ_CP126091:c1437281-1437108 [Bacillus paralicheniformis]
MEPAFQQDHESAKKRLAFKMFKKQSKTNIAKYEVSPHTERIFRQNERLIGEYKRKKA

Download         Length: 174 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6I7TYV7

Antitoxin

Source ID Structure
AlphaFold DB A0A6I7TM13

References