282593

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/MazF(toxin)
Location 278485..279124 Replicon chromosome
Accession NZ_CP126085
Organism Peribacillus frigoritolerans strain CF20

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag QNH33_RS01445 Protein ID WP_034306610.1
Coordinates 278774..279124 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag QNH33_RS01440 Protein ID WP_034306380.1
Coordinates 278485..278766 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QNH33_RS01420 (QNH33_01420) 274623..275213 - 591 WP_283906444.1 rhomboid family intramembrane serine protease -
QNH33_RS01425 (QNH33_01425) 275321..275671 + 351 WP_053537119.1 holo-ACP synthase -
QNH33_RS01430 (QNH33_01430) 275915..276919 + 1005 WP_053537120.1 outer membrane lipoprotein carrier protein LolA -
QNH33_RS01435 (QNH33_01435) 277137..278324 + 1188 WP_283907211.1 alanine racemase -
QNH33_RS01440 (QNH33_01440) 278485..278766 + 282 WP_034306380.1 antitoxin EndoAI Antitoxin
QNH33_RS01445 (QNH33_01445) 278774..279124 + 351 WP_034306610.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
QNH33_RS01450 (QNH33_01450) 279540..280367 + 828 WP_054398282.1 RsbT co-antagonist protein RsbRA -
QNH33_RS01455 (QNH33_01455) 280370..280726 + 357 WP_048682053.1 STAS domain-containing protein -
QNH33_RS01460 (QNH33_01460) 280730..281131 + 402 WP_053537122.1 anti-sigma regulatory factor -
QNH33_RS01465 (QNH33_01465) 281141..282151 + 1011 WP_264896145.1 PP2C family protein-serine/threonine phosphatase -
QNH33_RS01470 (QNH33_01470) 282211..282543 + 333 WP_034306369.1 anti-sigma factor antagonist -
QNH33_RS01475 (QNH33_01475) 282540..283013 + 474 WP_053537124.1 anti-sigma B factor RsbW -
QNH33_RS01480 (QNH33_01480) 282991..283779 + 789 WP_034306363.1 RNA polymerase sigma factor SigB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-113)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12955.06 Da        Isoelectric Point: 7.2029

>T282593 WP_034306610.1 NZ_CP126085:278774-279124 [Peribacillus frigoritolerans]
IVVKRGDVYFADLSPVVGSEQGGTRPVLILQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEINAKKYGFERDSVILLEQI
RTIDKQRLTDKITHLDEPMMQKVNEALQISLGLIEF

Download         Length: 351 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10713.13 Da        Isoelectric Point: 5.9054

>AT282593 WP_034306380.1 NZ_CP126085:278485-278766 [Peribacillus frigoritolerans]
VSESSATREILIRLPQNFLTELDGYASEENVNRSEFIYRATKMYLRERKKKEFRESMKRGYIEMAAINLTIASEAFQAEF
EAGHCVERLVSGG

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References