Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazF-pemI/MazF(toxin)
Location 4092553..4093188 Replicon chromosome
Accession NZ_CP126084
Organism Paenibacillus woosongensis strain B2_4

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag QNH46_RS18705 Protein ID WP_125082509.1
Coordinates 4092553..4092903 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag QNH46_RS18710 Protein ID WP_019638235.1
Coordinates 4092907..4093188 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QNH46_RS18690 (QNH46_18685) 4088761..4089480 - 720 WP_244996863.1 hypothetical protein -
QNH46_RS18695 (QNH46_18690) 4089622..4091850 - 2229 WP_283925572.1 Tex family protein -
QNH46_RS18700 (QNH46_18695) 4091985..4092347 - 363 WP_283925573.1 DUF4190 domain-containing protein -
QNH46_RS18705 (QNH46_18700) 4092553..4092903 - 351 WP_125082509.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
QNH46_RS18710 (QNH46_18705) 4092907..4093188 - 282 WP_019638235.1 ribbon-helix-helix protein, CopG family Antitoxin
QNH46_RS18715 (QNH46_18710) 4093445..4094629 - 1185 WP_283928495.1 alanine racemase -
QNH46_RS18720 (QNH46_18715) 4094854..4095951 - 1098 WP_283925574.1 outer membrane lipoprotein carrier protein LolA -
QNH46_RS18725 (QNH46_18720) 4096065..4096250 - 186 WP_283925575.1 hypothetical protein -
QNH46_RS18730 (QNH46_18725) 4096312..4096518 + 207 WP_283925576.1 hypothetical protein -
QNH46_RS18735 (QNH46_18730) 4096540..4097307 + 768 WP_283925577.1 methyl-accepting chemotaxis protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-113)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-46)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12820.83 Da        Isoelectric Point: 5.6195

>T282592 WP_125082509.1 NZ_CP126084:c4092903-4092553 [Paenibacillus woosongensis]
MIVKRGDVFFADLSPVVGSEQGGVRPVLIIQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIEAATHGFDRDSVILLEQI
RTIDKQRLTDKITHLDDETMKKVNDSLLISLGLIDF

Download         Length: 351 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10762.42 Da        Isoelectric Point: 6.4710

>AT282592 WP_019638235.1 NZ_CP126084:c4093188-4092907 [Paenibacillus woosongensis]
MANMQNTKRIMISLPDHLLQEVDGIVAMENSNRSELIRQAMKLYLNERKKRFIRESMQRGYMEMAKINLTMASEAFHAEE
DADSTLDRLVSGV

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References