Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Fic(toxin)
Location 6817869..6818440 Replicon chromosome
Accession NZ_CP126066
Organism Streptomyces sp. NA07423

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag QFW82_RS28190 Protein ID WP_079257839.1
Coordinates 6818066..6818440 (+) Length 125 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID A0A1P8XVF0
Locus tag QFW82_RS28185 Protein ID WP_069863663.1
Coordinates 6817869..6818066 (+) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QFW82_RS28165 (QFW82_28165) 6813284..6814189 + 906 WP_069863657.1 LysR family transcriptional regulator -
QFW82_RS28170 (QFW82_28170) 6814363..6814932 + 570 WP_079257842.1 cysteine dioxygenase family protein -
QFW82_RS28175 (QFW82_28175) 6814929..6816035 + 1107 WP_283886490.1 putative sulfate exporter family transporter -
QFW82_RS28180 (QFW82_28180) 6816342..6817835 + 1494 WP_283886491.1 MFS transporter -
QFW82_RS28185 (QFW82_28185) 6817869..6818066 + 198 WP_069863663.1 Arc family DNA-binding protein Antitoxin
QFW82_RS28190 (QFW82_28190) 6818066..6818440 + 375 WP_079257839.1 Fic family protein Toxin
QFW82_RS28195 (QFW82_28195) 6818552..6820348 + 1797 WP_283886492.1 DEAD/DEAH box helicase -
QFW82_RS28200 (QFW82_28200) 6821113..6821754 + 642 WP_069863676.1 helix-turn-helix domain-containing protein -
QFW82_RS28205 (QFW82_28205) 6821897..6822682 + 786 WP_283886493.1 S16 family serine protease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Fido domain

(11-80)

Antitoxin

Arc-like DNA binding domain

(4-42)


Sequences

Toxin        


Download         Length: 125 a.a.        Molecular weight: 14001.81 Da        Isoelectric Point: 4.7465

>T282542 WP_079257839.1 NZ_CP126066:6818066-6818440 [Streptomyces sp. NA07423]
MHYLTLPELLNLAERLGESEVRDYGLLESALARPQASVFGQDAYPDVWQKAAALMESSARNHALVDGNKRLSWYATWVFL
HINGHPLHADFDVDEAERFVLSVCQGELDVAKIAEGLTRFTERM

Download         Length: 375 bp

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7439.31 Da        Isoelectric Point: 5.6033

>AT282542 WP_069863663.1 NZ_CP126066:6817869-6818066 [Streptomyces sp. NA07423]
MAALNLRFTDEELDALRKRAEAEGRSMQSFAHDAVMAAINEHSRRFDEAADHVLRVSEELNRRLA

Download         Length: 198 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1P8XVF0

References