Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3343961..3344106 Replicon chromosome
Accession NZ_CP126058
Organism Klebsiella pneumoniae subsp. pneumoniae strain CS00491

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3343968..3344070 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3343961..3344106 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QM175_RS16140 3339494..3340927 + 1434 WP_283903520.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
QM175_RS16145 3341043..3341282 + 240 WP_002911393.1 YebV family protein -
QM175_RS16150 3341380..3341571 + 192 WP_002911395.1 YebW family protein -
QM175_RS16155 3341568..3342221 - 654 WP_004891053.1 protein-serine/threonine phosphatase -
QM175_RS16160 3342378..3343345 + 968 Protein_3150 VirK/YbjX family protein -
QM175_RS16165 3343450..3343593 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3343961..3344106 + 146 - - Antitoxin
- 3343968..3344070 - 103 - - Toxin
QM175_RS16170 3344229..3344567 - 339 WP_002911404.1 YebY family protein -
QM175_RS16175 3344584..3345453 - 870 WP_032435031.1 copper homeostasis membrane protein CopD -
QM175_RS16180 3345457..3345831 - 375 WP_004151448.1 CopC domain-containing protein YobA -
QM175_RS16185 3345944..3346174 + 231 WP_002911406.1 DNA polymerase III subunit theta -
QM175_RS16190 3346253..3346912 + 660 WP_032435029.1 exodeoxyribonuclease X -
QM175_RS16195 3346916..3348976 - 2061 WP_004148850.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T282534 NZ_CP126058:c3344070-3343968 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT282534 NZ_CP126058:3343961-3344106 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References