282520

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 5778765..5779381 Replicon chromosome
Accession NZ_CP125996
Organism Gordonia sp. L191

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QNM97_RS26090 Protein ID WP_208793031.1
Coordinates 5778765..5779172 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QNM97_RS26095 Protein ID WP_208793030.1
Coordinates 5779169..5779381 (-) Length 71 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QNM97_RS26070 (QNM97_26070) 5774288..5774806 + 519 WP_283823333.1 phenolic acid decarboxylase -
QNM97_RS26075 (QNM97_26075) 5774905..5775348 + 444 WP_283820968.1 DUF4186 domain-containing protein -
QNM97_RS26080 (QNM97_26080) 5775454..5776125 + 672 WP_283820969.1 alpha/beta hydrolase-fold protein -
QNM97_RS26085 (QNM97_26085) 5776343..5778682 + 2340 WP_283820970.1 endopeptidase La -
QNM97_RS26090 (QNM97_26090) 5778765..5779172 - 408 WP_208793031.1 PIN domain-containing protein Toxin
QNM97_RS26095 (QNM97_26095) 5779169..5779381 - 213 WP_208793030.1 CopG family transcriptional regulator Antitoxin
QNM97_RS26100 (QNM97_26100) 5779465..5779917 - 453 WP_283820971.1 hypothetical protein -
QNM97_RS26105 (QNM97_26105) 5779961..5781130 - 1170 WP_283820972.1 LLM class flavin-dependent oxidoreductase -
QNM97_RS26110 (QNM97_26110) 5781269..5781628 + 360 WP_208793027.1 hypothetical protein -
QNM97_RS26115 (QNM97_26115) 5781681..5782112 + 432 WP_283820973.1 hypothetical protein -
QNM97_RS26120 (QNM97_26120) 5782115..5782420 + 306 WP_283820974.1 DUF6036 family nucleotidyltransferase -
QNM97_RS26125 (QNM97_26125) 5782587..5783303 - 717 WP_283820975.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-118)

Antitoxin

Ribbon-helix-helix protein, CopG

(4-40)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 14613.66 Da        Isoelectric Point: 4.4922

>T282520 WP_208793031.1 NZ_CP125996:c5779172-5778765 [Gordonia sp. L191]
VILDTSALLAYFDSAEPQHSAVAEIIESHSGPLVISPFVIAELDYLLLTRHGTRAEQVVLSELTSGAWELASMTRSRIVT
ATAIVERYSDIPIGVTDASNIVLADAYQTSLIATLDHRHFSILRLMDGSPPTIVP

Download         Length: 408 bp

Antitoxin


Download         Length: 71 a.a.        Molecular weight: 7765.83 Da        Isoelectric Point: 4.8409

>AT282520 WP_208793030.1 NZ_CP125996:c5779381-5779169 [Gordonia sp. L191]
MAKTTLYLPDDLKRAIELEARRRSISEAEVVREALRAALDGQKPRPRGGLFVGSEPIAERAEELLDGFGE

Download         Length: 213 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References