Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /SpoIISA(toxin)
Location 2412081..2413056 Replicon chromosome
Accession NZ_CP125992
Organism Bacillus cereus strain FFI_gr_36

Toxin (Protein)


Gene name spoIISA Uniprot ID C3GJ28
Locus tag QM226_RS12380 Protein ID WP_003297560.1
Coordinates 2412081..2412818 (+) Length 246 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag QM226_RS12385 Protein ID WP_061686604.1
Coordinates 2412931..2413056 (+) Length 42 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QM226_RS12360 (QM226_002479) 2407809..2408591 + 783 WP_000381787.1 class I SAM-dependent methyltransferase -
QM226_RS12365 (QM226_002480) 2408713..2410398 - 1686 WP_283729851.1 alpha-keto acid decarboxylase family protein -
QM226_RS12370 (QM226_002481) 2410505..2410987 + 483 WP_000191912.1 MarR family winged helix-turn-helix transcriptional regulator -
QM226_RS12375 (QM226_002482) 2411155..2411892 + 738 WP_000594156.1 2,3-diphosphoglycerate-dependent phosphoglycerate mutase -
QM226_RS12380 (QM226_002483) 2412081..2412818 + 738 WP_003297560.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
QM226_RS12385 (QM226_002484) 2412931..2413056 + 126 WP_061686604.1 hypothetical protein Antitoxin
QM226_RS12390 (QM226_002485) 2413133..2413309 + 177 WP_000808046.1 stage II sporulation protein SB -
QM226_RS12395 (QM226_002486) 2413453..2414922 + 1470 WP_000287522.1 beta-Ala-His dipeptidase -
QM226_RS12400 (QM226_002487) 2415449..2415919 - 471 WP_029438359.1 DUF5065 family protein -
QM226_RS12405 (QM226_002488) 2416375..2417031 + 657 WP_075666799.1 CatB-related O-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(9-243)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 246 a.a.        Molecular weight: 28373.07 Da        Isoelectric Point: 8.2672

>T282517 WP_003297560.1 NZ_CP125992:2412081-2412818 [Bacillus cereus]
VISNIRIGLFILAIVFLILVFFYWKNEELYEEKKQRIRKTWYGLFIISVTVYFMIKGIDLTLWKNLLMFTAMVIFVDIAF
ILTPNISEIWGAKFSDIGKTVQSIKRSLIASKARGEIYTTIIQNVNPAVFGTMEWHTEEEYTKSLNAFLDSYGEKIGAKI
VVFEAAKELNTNFRGIRSQFSTIIPLEYIEQLNEQRAVQVENVGIIPAKIVSDVFIVIDGKKNNLQDRDFENVYNLTIHH
SYFSK

Download         Length: 738 bp

Antitoxin


Download         Length: 42 a.a.        Molecular weight: 4910.29 Da        Isoelectric Point: 3.8880

>AT282517 WP_061686604.1 NZ_CP125992:2412931-2413056 [Bacillus cereus]
VIKDYDNDFFKEDNEDTTDFSLIKGDTLQQVEDLEDELKRK

Download         Length: 126 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3R9EK80

Antitoxin

Source ID Structure

References