282515

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /SpoIISA(toxin)
Location 2328670..2329645 Replicon chromosome
Accession NZ_CP125989
Organism Bacillus cereus strain FFI_gr_46

Toxin (Protein)


Gene name spoIISA Uniprot ID -
Locus tag QM225_RS12070 Protein ID WP_283730748.1
Coordinates 2328670..2329407 (+) Length 246 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID R8HWP4
Locus tag QM225_RS12075 Protein ID WP_000588712.1
Coordinates 2329520..2329645 (+) Length 42 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QM225_RS12040 (QM225_002414) 2323745..2324455 + 711 WP_283730671.1 class I SAM-dependent methyltransferase -
QM225_RS12045 (QM225_002415) 2324575..2324982 + 408 WP_000072480.1 VOC family protein -
QM225_RS12050 (QM225_002416) 2325088..2325180 + 93 Protein_2291 methyltransferase -
QM225_RS12055 (QM225_002417) 2325302..2326987 - 1686 WP_283730672.1 alpha-keto acid decarboxylase family protein -
QM225_RS12060 (QM225_002418) 2327094..2327576 + 483 WP_000191911.1 MarR family winged helix-turn-helix transcriptional regulator -
QM225_RS12065 (QM225_002419) 2327744..2328481 + 738 WP_000594156.1 2,3-diphosphoglycerate-dependent phosphoglycerate mutase -
QM225_RS12070 (QM225_002420) 2328670..2329407 + 738 WP_283730748.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
QM225_RS12075 (QM225_002421) 2329520..2329645 + 126 WP_000588712.1 hypothetical protein Antitoxin
QM225_RS12080 (QM225_002422) 2329722..2329898 + 177 WP_000808045.1 stage II sporulation protein SB -
QM225_RS12085 (QM225_002423) 2330042..2331511 + 1470 WP_283730673.1 beta-Ala-His dipeptidase -
QM225_RS12090 (QM225_002424) 2331746..2332216 - 471 WP_000670597.1 DUF5065 family protein -
QM225_RS12095 (QM225_002425) 2332393..2333013 + 621 WP_002036390.1 SGNH/GDSL hydrolase family protein -
QM225_RS12100 (QM225_002426) 2333236..2333769 + 534 WP_000438322.1 sigma-70 family RNA polymerase sigma factor -
QM225_RS12105 (QM225_002427) 2333759..2334586 + 828 WP_001060391.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(9-243)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 246 a.a.        Molecular weight: 28345.02 Da        Isoelectric Point: 8.2672

>T282515 WP_283730748.1 NZ_CP125989:2328670-2329407 [Bacillus cereus]
VISNIRIGLFILAIVFLILVFFYWKNEELYEEKKQRIRKTWYGLFIISVTVYFMIKGIDLTLWKNLLMFTAMVIFVDIAF
ILTPNISEIWGAKFSDIGKTVQSIKRSLIASKARGEIYTTIIQNVNPAAFGTMEWHTEEEYTKSLNAFLDSYGEKIGAKI
VVFEAAKELNTNFRGIRSQFSTIIPLEYIEQLNEQRAVQVENVGIIPAKIVSDVFIVIDGKKNNLQDRDFENVYNLTIHH
SYFSK

Download         Length: 738 bp

Antitoxin


Download         Length: 42 a.a.        Molecular weight: 4938.34 Da        Isoelectric Point: 3.9150

>AT282515 WP_000588712.1 NZ_CP125989:2329520-2329645 [Bacillus cereus]
VIKDYDNDFFKEDNEDTTDFSLIKGDTLQQVEELEEELKRK

Download         Length: 126 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A366GQT1

References