Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PP_4151-4152/excise(antitoxin) |
| Location | 24674..25682 | Replicon | plasmid unnamed |
| Accession | NZ_CP125988 | ||
| Organism | Myroides odoratimimus strain 31 | ||
Toxin (Protein)
| Gene name | PP_4152 | Uniprot ID | - |
| Locus tag | QK342_RS17935 | Protein ID | WP_131541122.1 |
| Coordinates | 25119..25682 (+) | Length | 188 a.a. |
Antitoxin (Protein)
| Gene name | PP_4151 | Uniprot ID | - |
| Locus tag | QK342_RS17930 | Protein ID | WP_131541121.1 |
| Coordinates | 24674..25129 (+) | Length | 152 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QK342_RS17900 (QK342_17900) | 20595..21392 | + | 798 | WP_131541115.1 | hypothetical protein | - |
| QK342_RS17905 (QK342_17905) | 21628..21804 | + | 177 | WP_131541116.1 | histone H1 | - |
| QK342_RS17910 (QK342_17910) | 22002..22340 | + | 339 | WP_131541117.1 | hypothetical protein | - |
| QK342_RS17915 (QK342_17915) | 22343..22807 | - | 465 | WP_131541118.1 | S24 family peptidase | - |
| QK342_RS17920 (QK342_17920) | 22804..24057 | - | 1254 | WP_131541119.1 | Y-family DNA polymerase | - |
| QK342_RS17925 (QK342_17925) | 24103..24558 | + | 456 | WP_131541120.1 | hypothetical protein | - |
| QK342_RS17930 (QK342_17930) | 24674..25129 | + | 456 | WP_131541121.1 | helix-turn-helix domain-containing protein | Antitoxin |
| QK342_RS17935 (QK342_17935) | 25119..25682 | + | 564 | WP_131541122.1 | PIN domain-containing protein | Toxin |
| QK342_RS17940 (QK342_17940) | 25808..26371 | + | 564 | WP_131541123.1 | recombinase family protein | - |
| QK342_RS17945 (QK342_17945) | 26427..26816 | + | 390 | WP_131541124.1 | hypothetical protein | - |
| QK342_RS17950 (QK342_17950) | 26821..27810 | + | 990 | WP_131541125.1 | WYL domain-containing protein | - |
| QK342_RS17955 (QK342_17955) | 27871..30327 | + | 2457 | WP_131541126.1 | N-6 DNA methylase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..43223 | 43223 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 188 a.a. Molecular weight: 21440.74 Da Isoelectric Point: 5.2668
>T282513 WP_131541122.1 NZ_CP125988:25119-25682 [Myroides odoratimimus]
MIHSVRYKAVLDTNVIFPIVIRDLLFWFAHYDLYTPKWSKIIFDEWKSVMIRKGVESSQAEKRINVANLAFPDALVLNYE
GLIDNLNLPDKDDRHVLAAAIKVNANIIVTNNLKDFPDDYLDSFGLKAVCADDFLTDIIDLNPKIALQAFKDLVLNRKNP
AMDEFQVLESFRKNGLNQTADYLHALL
MIHSVRYKAVLDTNVIFPIVIRDLLFWFAHYDLYTPKWSKIIFDEWKSVMIRKGVESSQAEKRINVANLAFPDALVLNYE
GLIDNLNLPDKDDRHVLAAAIKVNANIIVTNNLKDFPDDYLDSFGLKAVCADDFLTDIIDLNPKIALQAFKDLVLNRKNP
AMDEFQVLESFRKNGLNQTADYLHALL
Download Length: 564 bp
Antitoxin
Download Length: 152 a.a. Molecular weight: 17423.16 Da Isoelectric Point: 5.7617
>AT282513 WP_131541121.1 NZ_CP125988:24674-25129 [Myroides odoratimimus]
METLDYIKRPTKKEQRVAIESYSALSSILSQLKNDDTEIEIEETNDRIKIPFKALKLLSEILKSMSEGNPISIVPIATEV
TTQKAAEILGCSRPHLVKLLEQGEIDFTMVGRHRRILFEDVIKYKNEMKQKQKKHIIDIMNFDDEIGLYDS
METLDYIKRPTKKEQRVAIESYSALSSILSQLKNDDTEIEIEETNDRIKIPFKALKLLSEILKSMSEGNPISIVPIATEV
TTQKAAEILGCSRPHLVKLLEQGEIDFTMVGRHRRILFEDVIKYKNEMKQKQKKHIIDIMNFDDEIGLYDS
Download Length: 456 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|