Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 5326767..5327366 Replicon chromosome
Accession NZ_CP125986
Organism Pseudomonas rhodesiae strain 3.8

Toxin (Protein)


Gene name relE Uniprot ID A0A5C5P148
Locus tag QMY54_RS27370 Protein ID WP_034095668.1
Coordinates 5326767..5327072 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A8I1E6D6
Locus tag QMY54_RS27375 Protein ID WP_034095667.1
Coordinates 5327076..5327366 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMY54_RS27350 (QMY54_05453) 5322380..5323006 - 627 WP_284184948.1 precorrin-8X methylmutase -
QMY54_RS27355 (QMY54_05454) 5322999..5324288 - 1290 WP_284184949.1 precorrin-3B synthase -
QMY54_RS27360 (QMY54_05455) 5324384..5325589 + 1206 WP_284184950.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE -
QMY54_RS27365 (QMY54_05456) 5325586..5326320 + 735 WP_220698556.1 cobalt-precorrin-6A reductase -
QMY54_RS27370 (QMY54_05457) 5326767..5327072 + 306 WP_034095668.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QMY54_RS27375 (QMY54_05458) 5327076..5327366 + 291 WP_034095667.1 putative addiction module antidote protein Antitoxin
QMY54_RS27380 (QMY54_05459) 5327464..5327886 + 423 WP_284184951.1 DUF2946 domain-containing protein -
QMY54_RS27385 (QMY54_05460) 5327907..5328389 + 483 WP_284184952.1 copper chaperone PCu(A)C -
QMY54_RS27390 (QMY54_05461) 5328401..5328802 + 402 WP_034095664.1 DUF2946 domain-containing protein -
QMY54_RS27395 (QMY54_05462) 5328896..5330956 + 2061 WP_284184953.1 TonB-dependent copper receptor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-97)

Antitoxin

Uncharacterized protein HI1420

(8-94)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11640.25 Da        Isoelectric Point: 5.8918

>T282512 WP_034095668.1 NZ_CP125986:5326767-5327072 [Pseudomonas rhodesiae]
MTIEFNETIEFANWLEAVRDPFVKVRVVKRVRMAEAGNFGDCESVGDGVFEMRIHYGPGYRVYFTRRDEVVYLLLIGGDK
STQSRDIKRAKQIAINFGSEE

Download         Length: 306 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10404.99 Da        Isoelectric Point: 5.8124

>AT282512 WP_034095667.1 NZ_CP125986:5327076-5327366 [Pseudomonas rhodesiae]
MSESFSRFDAAKYLKTPLEMAAYLETCFEDDAGDGLLIRTALNDIARAQGMTQVARDAGLGRESLYKALSSSGNPEFATI
MKVMKALGLKLHATVI

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A5C5P148

Antitoxin

Source ID Structure

References