Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicA(toxin)
Location 3634016..3634626 Replicon chromosome
Accession NZ_CP125986
Organism Pseudomonas rhodesiae strain 3.8

Toxin (Protein)


Gene name hicA Uniprot ID A0A2G0WYT7
Locus tag QMY54_RS19415 Protein ID WP_034096965.1
Coordinates 3634016..3634267 (+) Length 84 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag QMY54_RS19420 Protein ID WP_034096964.1
Coordinates 3634264..3634626 (+) Length 121 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMY54_RS19415 (QMY54_03872) 3634016..3634267 + 252 WP_034096965.1 type II toxin-antitoxin system HicA family toxin Toxin
QMY54_RS19420 (QMY54_03873) 3634264..3634626 + 363 WP_034096964.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
QMY54_RS19425 (QMY54_03874) 3634631..3635803 - 1173 WP_047883050.1 MFS transporter -
QMY54_RS19430 (QMY54_03875) 3635845..3637200 - 1356 WP_040268007.1 MATE family efflux transporter -
QMY54_RS19435 (QMY54_03876) 3637304..3638134 - 831 WP_213549373.1 IclR family transcriptional regulator -
QMY54_RS19440 (QMY54_03877) 3638378..3639406 + 1029 WP_034096960.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(20-76)

Antitoxin

Uncharacterised protein family HicB

(55-105)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9497.05 Da        Isoelectric Point: 10.0458

>T282511 WP_034096965.1 NZ_CP125986:3634016-3634267 [Pseudomonas rhodesiae]
VSKNEKLLAKLLNEQMAFTWPELVTLLRRLGYTQIEGAGSRVKFDSGDPTAMITLHKPHPGNELKHYIRRQIIEQLKSGE
LIQ

Download         Length: 252 bp

Antitoxin


Download         Length: 121 a.a.        Molecular weight: 13134.99 Da        Isoelectric Point: 7.0377

>AT282511 WP_034096964.1 NZ_CP125986:3634264-3634626 [Pseudomonas rhodesiae]
VNNQLKHKGYIGSIEASLEDNCLFGKILFIKALISYEGKTVADLDAAFQAAVDDYLVTCQNLGQTPEKPCKGSFNVRVGH
DLHLAAALAATRKKVTLNDLTRQALSEFLQHHFAELHPSA

Download         Length: 363 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2G0WYT7

Antitoxin

Source ID Structure

References