282509

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) BrnTA/BrnT_toxin-BrnA
Location 1722736..1723240 Replicon chromosome
Accession NZ_CP125986
Organism Pseudomonas rhodesiae strain 3.8

Toxin (Protein)


Gene name brnT Uniprot ID A0A2G0X8I2
Locus tag QMY54_RS10860 Protein ID WP_047881292.1
Coordinates 1722736..1722975 (+) Length 80 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID A0A2G0X8Q6
Locus tag QMY54_RS10865 Protein ID WP_034114783.1
Coordinates 1722992..1723240 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMY54_RS10835 (QMY54_02167) 1717828..1718949 + 1122 WP_034099658.1 beta-ketoacyl-ACP synthase III -
QMY54_RS10840 (QMY54_02168) 1718966..1719580 + 615 WP_034114785.1 RNA polymerase sigma factor -
QMY54_RS10845 (QMY54_02169) 1719574..1719819 + 246 WP_034099654.1 zf-HC2 domain-containing protein -
QMY54_RS10850 (QMY54_02170) 1719927..1721249 - 1323 WP_034099652.1 putative porin -
QMY54_RS10855 (QMY54_02171) 1721534..1722658 + 1125 WP_034099861.1 GNAT family N-acetyltransferase -
QMY54_RS10860 (QMY54_02172) 1722736..1722975 + 240 WP_047881292.1 BrnT family toxin Toxin
QMY54_RS10865 (QMY54_02173) 1722992..1723240 + 249 WP_034114783.1 BrnA antitoxin family protein Antitoxin
QMY54_RS10870 (QMY54_02174) 1723312..1724013 - 702 WP_034099649.1 aquaporin Z -
QMY54_RS10875 (QMY54_02175) 1724161..1725993 - 1833 WP_034099647.1 ABC transporter ATP-binding protein -
QMY54_RS10880 (QMY54_02176) 1726076..1726639 - 564 WP_284185260.1 peptidylprolyl isomerase -
QMY54_RS10885 (QMY54_02177) 1726643..1727446 - 804 WP_047881295.1 alpha/beta hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-79)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(24-77)


Sequences

Toxin        


Download         Length: 80 a.a.        Molecular weight: 9353.79 Da        Isoelectric Point: 7.8593

>T282509 WP_047881292.1 NZ_CP125986:1722736-1722975 [Pseudomonas rhodesiae]
MRFEWDESKNKVNISKHGIDFNDVPDIFRHPMLALRDDRADYGEERWICIGWIKRLMGVVVYTERCGDVIRIISARKAT

Download         Length: 240 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9642.95 Da        Isoelectric Point: 7.0124

>AT282509 WP_034114783.1 NZ_CP125986:1722992-1723240 [Pseudomonas rhodesiae]
MTQTSKTDWERLAKMKDKEIDTSDIPELDAEFFRRAELRVPVKQAVTIRLDADVLEWFKGQGTGYQTRINQLLRQYMQAH
QG

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2G0X8I2

Antitoxin

Source ID Structure
AlphaFold DB A0A2G0X8Q6

References