282507

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907-MazE
Location 2818819..2819417 Replicon chromosome
Accession NZ_CP125968
Organism Sporosarcina thermotolerans strain CCUG 53480

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag QNH10_RS15955 Protein ID WP_283732330.1
Coordinates 2818819..2819160 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag QNH10_RS15960 Protein ID WP_283732331.1
Coordinates 2819157..2819417 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QNH10_RS15935 (QNH10_15935) 2814515..2815783 - 1269 WP_283732327.1 ATP-dependent protease ATP-binding subunit ClpX -
QNH10_RS15940 (QNH10_15940) 2815931..2817216 - 1286 Protein_3083 trigger factor -
QNH10_RS15945 (QNH10_15945) 2817342..2817518 - 177 WP_283732328.1 hypothetical protein -
QNH10_RS15950 (QNH10_15950) 2817479..2818309 - 831 WP_283732329.1 tetratricopeptide repeat protein -
QNH10_RS15955 (QNH10_15955) 2818819..2819160 - 342 WP_283732330.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
QNH10_RS15960 (QNH10_15960) 2819157..2819417 - 261 WP_283732331.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
QNH10_RS15965 (QNH10_15965) 2819587..2820069 - 483 Protein_3088 thiamine pyrophosphate-dependent enzyme -
QNH10_RS15970 (QNH10_15970) 2820800..2821621 - 822 WP_283732333.1 cupin domain-containing protein -
QNH10_RS15975 (QNH10_15975) 2822184..2823293 - 1110 WP_283732334.1 hypothetical protein -
QNH10_RS15980 (QNH10_15980) 2823626..2824291 - 666 WP_283732335.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(7-106)

Antitoxin

SpoVT-AbrB domain

(13-58)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12620.40 Da        Isoelectric Point: 4.5821

>T282507 WP_283732330.1 NZ_CP125968:c2819160-2818819 [Sporosarcina thermotolerans]
MTQVPNRGDLVYLNFSPQSGHEQRGRRPAIVLSPKSFNDLTGFSVVCPITTQQKGYPFEVEIPYGLAINGVILTDQVKSL
DWRSRGLNIEGQAPEETIIECLNLISTFLLIEE

Download         Length: 342 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9447.91 Da        Isoelectric Point: 7.3197

>AT282507 WP_283732331.1 NZ_CP125968:c2819417-2819157 [Sporosarcina thermotolerans]
MNPIRGGVVVKVQKWGNSLGLRIPATIAQQVNISEGTEVVLSVDTNQTLVVKPLKKKPTLEELLAKITPENKHHEIDFGT
EGNEHI

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References