282504

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 582238..582862 Replicon chromosome
Accession NZ_CP125966
Organism Helicobacter pylori strain H390r

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QM974_RS02810 Protein ID WP_271331027.1
Coordinates 582596..582862 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QM974_RS02805 Protein ID WP_271331026.1
Coordinates 582238..582615 (+) Length 126 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QM974_RS02775 (QM974_02775) 577382..578493 + 1112 Protein_528 hydrogenase formation protein HypD -
QM974_RS02780 (QM974_02780) 578444..579070 - 627 WP_271331024.1 helicase DnaB modulator -
QM974_RS02795 (QM974_02795) 579481..581706 + 2226 WP_283722679.1 Hop family adhesin BabA -
QM974_RS02800 (QM974_02800) 581654..581959 - 306 WP_283722680.1 hypothetical protein -
QM974_RS02805 (QM974_02805) 582238..582615 + 378 WP_271331026.1 hypothetical protein Antitoxin
QM974_RS02810 (QM974_02810) 582596..582862 + 267 WP_271331027.1 type II toxin-antitoxin system YafQ family toxin Toxin
QM974_RS02815 (QM974_02815) 582941..583252 + 312 WP_180669626.1 type II toxin-antitoxin system antitoxin -
QM974_RS02820 (QM974_02820) 583239..583511 + 273 WP_271331028.1 type II toxin-antitoxin system YafQ family toxin -
QM974_RS02825 (QM974_02825) 583617..584141 - 525 WP_001120212.1 acyl-CoA thioesterase -
QM974_RS02830 (QM974_02830) 584284..585126 + 843 WP_271331029.1 SDR family oxidoreductase -
QM974_RS02835 (QM974_02835) 585119..586099 + 981 WP_000921438.1 iron ABC transporter permease -
QM974_RS02840 (QM974_02840) 586099..586866 + 768 WP_024422093.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10235.10 Da        Isoelectric Point: 9.9517

>T282504 WP_271331027.1 NZ_CP125966:582596-582862 [Helicobacter pylori]
VLKLNLKKSFQKDFDKLLLNGFDDSVLNKVILSLRKKEPLGSQFQDHALKGKWKPFRECHIKADILLVYLVKDDELILVR
LGSHSELF

Download         Length: 267 bp

Antitoxin


Download         Length: 126 a.a.        Molecular weight: 14699.62 Da        Isoelectric Point: 7.8469

>AT282504 WP_271331026.1 NZ_CP125966:582238-582615 [Helicobacter pylori]
MPNSPTKKDYTQYSEKQLFNLIHQLEQKIKRMQNDRASFKEKMAKELEKRDQNFKDKIDALNELLQKISQAFDNKRDCCL
GHKIPNIETQQAMRDALNKETDLIVDDFSSYSDERKKALGVETQS

Download         Length: 378 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References