Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1576596..1577143 Replicon chromosome
Accession NZ_CP125961
Organism Pseudomonas brassicacearum strain R401

Toxin (Protein)


Gene name relE Uniprot ID G8Q8L6
Locus tag QLH64_RS07010 Protein ID WP_014337667.1
Coordinates 1576596..1576871 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID G8Q8L7
Locus tag QLH64_RS07015 Protein ID WP_014337668.1
Coordinates 1576871..1577143 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QLH64_RS06990 (QLH64_06990) 1572943..1573572 + 630 WP_014337664.1 isochorismate family cysteine hydrolase YcaC -
QLH64_RS06995 (QLH64_06995) 1573813..1574691 + 879 WP_057450026.1 LysR family transcriptional regulator -
QLH64_RS07000 (QLH64_07000) 1574748..1575224 - 477 WP_003203396.1 hemerythrin domain-containing protein -
QLH64_RS07005 (QLH64_07005) 1575423..1576532 - 1110 WP_057450024.1 NAD(P)/FAD-dependent oxidoreductase -
QLH64_RS07010 (QLH64_07010) 1576596..1576871 - 276 WP_014337667.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QLH64_RS07015 (QLH64_07015) 1576871..1577143 - 273 WP_014337668.1 ribbon-helix-helix domain-containing protein Antitoxin
QLH64_RS07020 (QLH64_07020) 1577560..1578027 + 468 WP_057450109.1 GNAT family N-acetyltransferase -
QLH64_RS07025 (QLH64_07025) 1578056..1578592 - 537 WP_057450023.1 DUF2867 domain-containing protein -
QLH64_RS07030 (QLH64_07030) 1578616..1579260 - 645 WP_057450107.1 DJ-1/PfpI family protein -
QLH64_RS07035 (QLH64_07035) 1579387..1579941 + 555 WP_003203390.1 TetR/AcrR family transcriptional regulator -
QLH64_RS07040 (QLH64_07040) 1580064..1581527 - 1464 WP_003203388.1 NADH-quinone oxidoreductase subunit NuoN -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(10-47)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10619.17 Da        Isoelectric Point: 9.5555

>T282500 WP_014337667.1 NZ_CP125961:c1576871-1576596 [Pseudomonas brassicacearum]
MELKWTSKALSDIARLYEFLAAVNQPAAARTVQQLTAAPTSLLANPRIGERLEEFEPRDVRRIQVGRYEMRYEIAGSTLY
LLRLWHTREDR

Download         Length: 276 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10108.40 Da        Isoelectric Point: 6.0741

>AT282500 WP_014337668.1 NZ_CP125961:c1577143-1576871 [Pseudomonas brassicacearum]
MTTTAKTRSVTAHVPVHLAEKVDLMAERLERSRNWIVKQALSAWIEQEEERSRLTHEALADVDAGRVIDHQAVQAWADSL
STDAPLPVPR

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB G8Q8L6

Antitoxin

Source ID Structure
AlphaFold DB G8Q8L7

References