Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 2200305..2200852 Replicon chromosome
Accession NZ_CP125957
Organism Pseudomonas sp. G2-4

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QNH97_RS09910 Protein ID WP_283556642.1
Coordinates 2200577..2200852 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID J2F8D1
Locus tag QNH97_RS09905 Protein ID WP_003179778.1
Coordinates 2200305..2200577 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QNH97_RS09870 (QNH97_09870) 2195342..2195902 + 561 WP_030142022.1 CvpA family protein -
QNH97_RS09875 (QNH97_09875) 2195944..2197449 + 1506 WP_025212828.1 amidophosphoribosyltransferase -
QNH97_RS09880 (QNH97_09880) 2197508..2198719 + 1212 WP_025212829.1 O-succinylhomoserine sulfhydrylase -
QNH97_RS09885 (QNH97_09885) 2198716..2199489 + 774 WP_283556641.1 SDR family oxidoreductase -
QNH97_RS09905 (QNH97_09905) 2200305..2200577 + 273 WP_003179778.1 ribbon-helix-helix domain-containing protein Antitoxin
QNH97_RS09910 (QNH97_09910) 2200577..2200852 + 276 WP_283556642.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QNH97_RS09915 (QNH97_09915) 2200889..2202172 - 1284 WP_283556643.1 FAD-binding oxidoreductase -
QNH97_RS09925 (QNH97_09925) 2202517..2203161 + 645 WP_025212832.1 hypothetical protein -
QNH97_RS09930 (QNH97_09930) 2203766..2204272 + 507 WP_283556644.1 AAA family ATPase -
QNH97_RS09935 (QNH97_09935) 2204452..2204724 + 273 WP_283556645.1 hypothetical protein -
QNH97_RS09940 (QNH97_09940) 2204979..2205257 + 279 WP_283556646.1 hypothetical protein -
QNH97_RS09945 (QNH97_09945) 2205272..2205442 - 171 WP_283556647.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(10-47)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10741.34 Da        Isoelectric Point: 9.5859

>T282496 WP_283556642.1 NZ_CP125957:2200577-2200852 [Pseudomonas sp. G2-4]
MELKWTSRALSDISRLYEFLAAVNQPAAARTVQQLTAAPITLLTNPRIGERLEEFEPRGVRRIQIGHYEMRYEIIDSTVY
LLRLWHTRENR

Download         Length: 276 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10125.40 Da        Isoelectric Point: 5.1007

>AT282496 WP_003179778.1 NZ_CP125957:2200305-2200577 [Pseudomonas sp. G2-4]
MATTTKTRSVTAHVPEQLAQKVDLMAERLERSKNWIVKQALSAWIDQEEERSRMTHEALADVDAGRVIDQQAVQAWADSL
STDTPLPVPR

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB J2F8D1

References