Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-PumB/upstrm_HI1419-dnstrm_HI1420
Location 3143556..3144174 Replicon chromosome
Accession NZ_CP125947
Organism Comamonas sp. ZM22

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QMY55_RS14620 Protein ID WP_283484921.1
Coordinates 3143878..3144174 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag QMY55_RS14615 Protein ID WP_283484920.1
Coordinates 3143556..3143873 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMY55_RS14585 (QMY55_14585) 3138616..3139311 + 696 WP_283484914.1 hypothetical protein -
QMY55_RS14590 (QMY55_14590) 3139511..3139882 + 372 WP_283484915.1 type I restriction endonuclease subunit M -
QMY55_RS14595 (QMY55_14595) 3139882..3140613 + 732 WP_283484916.1 hypothetical protein -
QMY55_RS14600 (QMY55_14600) 3140619..3141014 - 396 WP_283484917.1 helix-turn-helix transcriptional regulator -
QMY55_RS14605 (QMY55_14605) 3141116..3142258 + 1143 WP_283484918.1 hypothetical protein -
QMY55_RS14610 (QMY55_14610) 3142439..3143488 + 1050 WP_283484919.1 dienelactone hydrolase family protein -
QMY55_RS14615 (QMY55_14615) 3143556..3143873 - 318 WP_283484920.1 putative addiction module antidote protein Antitoxin
QMY55_RS14620 (QMY55_14620) 3143878..3144174 - 297 WP_283484921.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QMY55_RS14625 (QMY55_14625) 3144358..3145506 - 1149 WP_283484922.1 phage/plasmid replication protein -
QMY55_RS14630 (QMY55_14630) 3145674..3146615 - 942 WP_283484923.1 AAA family ATPase -
QMY55_RS14635 (QMY55_14635) 3146720..3147007 - 288 WP_283484924.1 hypothetical protein -
QMY55_RS14640 (QMY55_14640) 3147528..3148055 + 528 Protein_2847 DUF45 domain-containing protein -
QMY55_RS14645 (QMY55_14645) 3148393..3149103 - 711 WP_283484925.1 DUF6499 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3137278..3159766 22488


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-97)

Antitoxin

Uncharacterized protein HI1420

(13-98)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 10730.39 Da        Isoelectric Point: 9.7118

>T282490 WP_283484921.1 NZ_CP125947:c3144174-3143878 [Comamonas sp. ZM22]
MIQVLRTAAFDDWLQALRDKVGQRQVLARLTRLSLGNWGDCKPVGGEVTELRIDSGPGYRVYCWRAGDVVVVALGGGDKS
TQQKDIAKAQAMVKELKG

Download         Length: 297 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11325.97 Da        Isoelectric Point: 5.5865

>AT282490 WP_283484920.1 NZ_CP125947:c3143873-3143556 [Comamonas sp. ZM22]
MNRAAYEKLGIKPFDAAEYLQSDEDCAAYLQACLEQAPDDAAVFTKALGDIARARGMMQLAKDTGLTREGLYKSLGEQGN
PSLSTVMKVMHALGLQMHIGPHTPA

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References