Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 336691..337346 Replicon chromosome
Accession NZ_CP125879
Organism Auritidibacter ignavus strain BABAE-8

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QM395_RS01460 Protein ID WP_110100005.1
Coordinates 336691..337116 (-) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QM395_RS01465 Protein ID WP_110100006.1
Coordinates 337113..337346 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QM395_RS01420 (QM395_01420) 332330..333094 - 765 WP_283518357.1 sulfite exporter TauE/SafE family protein -
QM395_RS01425 (QM395_01425) 333360..333734 - 375 WP_283518359.1 hypothetical protein -
QM395_RS01430 (QM395_01430) 333719..334003 - 285 WP_283518361.1 hypothetical protein -
QM395_RS01435 (QM395_01435) 334103..334408 - 306 WP_110100035.1 helix-turn-helix transcriptional regulator -
QM395_RS01440 (QM395_01440) 334414..334605 - 192 WP_233242926.1 type II toxin-antitoxin system RelE/ParE family toxin -
QM395_RS01445 (QM395_01445) 334872..335597 - 726 WP_283518363.1 hypothetical protein -
QM395_RS01450 (QM395_01450) 336141..336389 - 249 WP_283518365.1 hypothetical protein -
QM395_RS01455 (QM395_01455) 336394..336678 - 285 WP_283518367.1 hypothetical protein -
QM395_RS01460 (QM395_01460) 336691..337116 - 426 WP_110100005.1 type II toxin-antitoxin system VapC family toxin Toxin
QM395_RS01465 (QM395_01465) 337113..337346 - 234 WP_110100006.1 Arc family DNA-binding protein Antitoxin
QM395_RS01470 (QM395_01470) 337494..338579 - 1086 WP_283518370.1 redox-regulated ATPase YchF -
QM395_RS01475 (QM395_01475) 338874..341081 + 2208 WP_283518372.1 choline BCCT transporter BetT -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-128)

Antitoxin

Arc-like DNA binding domain

(13-40)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15267.47 Da        Isoelectric Point: 5.2123

>T282414 WP_110100005.1 NZ_CP125879:c337116-336691 [Auritidibacter ignavus]
VIILDTNVISEIFRPLPEPRVADWLTSLEGDVAITSVTLAELLAGLRRLPDGRRRDALTRRIDVALAPYRGGRAVLPFDD
VAADRYADVLVARERAGAPISTADAQIAAICLAHGATCATRNVKDFQHTGVELVDPWKVDA

Download         Length: 426 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8242.47 Da        Isoelectric Point: 5.6643

>AT282414 WP_110100006.1 NZ_CP125879:c337346-337113 [Auritidibacter ignavus]
MSSIIVRGLDDAVKQQLAAQAKEHGRSMEAEVRAILTKAARRPHIGIALLAAAQDVGGVEELPIPVRDDVARAVDFE

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References