Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relE-stbD/ParE-YafN
Location 1521479..1522017 Replicon chromosome
Accession NZ_CP125805
Organism Mannheimia bovis strain 39324.S-11

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QMO40_RS07365 Protein ID WP_283385805.1
Coordinates 1521730..1522017 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name stbD Uniprot ID -
Locus tag QMO40_RS07360 Protein ID WP_283385804.1
Coordinates 1521479..1521733 (+) Length 85 a.a.

Genomic Context


QMO40_RS07340QMO40_RS07345QMO40_RS07350QMO40_RS07355QMO40_RS07360QMO40_RS07365QMO40_RS07375QMO40_RS07385QMO40_RS07390QMO40_RS07370QMO40_RS07380
Location: 1516603..1518066 (1464 bp)
Type: Others
Protein ID: WP_283385800.1
Location: 1518150..1518809 (660 bp)
Type: Others
Protein ID: WP_283385801.1
Location: 1518841..1519776 (936 bp)
Type: Others
Protein ID: WP_283385802.1
Location: 1519787..1521358 (1572 bp)
Type: Others
Protein ID: WP_283385803.1
Location: 1521479..1521733 (255 bp)
Type: Antitoxin
Protein ID: WP_283385804.1
Location: 1521730..1522017 (288 bp)
Type: Toxin
Protein ID: WP_283385805.1
Location: 1522398..1522919 (522 bp)
Type: Others
Protein ID: WP_283385807.1
Location: 1524627..1525715 (1089 bp)
Type: Others
Protein ID: WP_283385809.1
Location: 1525829..1526455 (627 bp)
Type: Others
Protein ID: WP_025236107.1
Location: 1522054..1522287 (234 bp)
Type: Others
Protein ID: WP_283385806.1
Location: 1522985..1524349 (1365 bp)
Type: Others
Protein ID: WP_283385808.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
QMO40_RS07340 (QMO40_07340)1516603..1518066+1464WP_283385800.1IMP dehydrogenase-
QMO40_RS07345 (QMO40_07345)1518150..1518809+660WP_283385801.1HAD family phosphatase-
QMO40_RS07350 (QMO40_07350)1518841..1519776+936WP_283385802.1DUF2806 domain-containing protein-
QMO40_RS07355 (QMO40_07355)1519787..1521358+1572WP_283385803.1glutamine-hydrolyzing GMP synthase-
QMO40_RS07360 (QMO40_07360)1521479..1521733+255WP_283385804.1plasmid stabilization proteinAntitoxin
QMO40_RS07365 (QMO40_07365)1521730..1522017+288WP_283385805.1type II toxin-antitoxin system RelE/ParE family toxinToxin
QMO40_RS07370 (QMO40_07370)1522054..1522287-234WP_283385806.1helix-turn-helix transcriptional regulator-
QMO40_RS07375 (QMO40_07375)1522398..1522919+522WP_283385807.1hypothetical protein-
QMO40_RS07380 (QMO40_07380)1522985..1524349-1365WP_283385808.1bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU-
QMO40_RS07385 (QMO40_07385)1524627..1525715+1089WP_283385809.1ionic transporter y4hA-
QMO40_RS07390 (QMO40_07390)1525829..1526455+627WP_025236107.123S rRNA (uridine(2552)-2'-O)-methyltransferase RlmE-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(2-84)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 96 a.a.        Molecular weight: 11329.35 Da        Isoelectric Point: 10.6648

>T282402 WP_283385805.1 NZ_CP125805:1521730-1522017 [Mannheimia bovis]
MKYTIEFIKSSEKEFRKLDLALRKQFVEKLKERAENPRVESAKLRGMKDCYKIKLRNSGYRLVYQVIDDRVVVKVIAVGK
RERNDVYQKASMRLS

Download         Length: 288 bp


Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9498.92 Da        Isoelectric Point: 4.0329

>AT282402 WP_283385804.1 NZ_CP125805:1521479-1521733 [Mannheimia bovis]
MPNIILTNTVASITELKTNPMATMRAAAGEPIAILNRNEPAFYCVPPHIYEYLMELADDAELAKIVEERQFEESYEIELA
DLLK

Download         Length: 255 bp


Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References